Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2047765..2047909 Replicon chromosome
Accession NZ_CP103420
Organism Klebsiella variicola strain KV1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2047801..2047903 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2047765..2047909 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYO12_RS10320 2042895..2044955 + 2061 WP_259073933.1 oligopeptidase B -
NYO12_RS10325 2044959..2045618 - 660 WP_008804267.1 exodeoxyribonuclease X -
NYO12_RS10330 2045697..2045927 - 231 WP_012541260.1 DNA polymerase III subunit theta -
NYO12_RS10335 2046041..2046415 + 375 WP_012541261.1 CopC domain-containing protein YobA -
NYO12_RS10340 2046419..2047288 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
NYO12_RS10345 2047305..2047643 + 339 WP_259073934.1 YebY family protein -
- 2047765..2047909 - 145 - - Antitoxin
- 2047801..2047903 + 103 - - Toxin
NYO12_RS10350 2048350..2049044 + 695 WP_110192083.1 IS1 family transposase -
NYO12_RS10355 2049062..2049205 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
NYO12_RS10360 2049309..2050277 - 969 WP_162493241.1 VirK/YbjX family protein -
NYO12_RS10365 2050434..2051087 + 654 WP_259073937.1 protein-serine/threonine phosphatase -
NYO12_RS10370 2051084..2051275 - 192 WP_002911395.1 YebW family protein -
NYO12_RS10375 2051373..2051612 - 240 WP_002911393.1 YebV family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255032 NZ_CP103420:2047801-2047903 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT255032 NZ_CP103420:c2047909-2047765 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References