Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1958258..1958402 Replicon chromosome
Accession NZ_CP103419
Organism Klebsiella variicola strain KV4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1958294..1958396 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1958258..1958402 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYO13_RS09405 (NYO13_09405) 1953388..1955448 + 2061 WP_048330475.1 oligopeptidase B -
NYO13_RS09410 (NYO13_09410) 1955452..1956111 - 660 WP_008804267.1 exodeoxyribonuclease X -
NYO13_RS09415 (NYO13_09415) 1956190..1956420 - 231 WP_012541260.1 DNA polymerase III subunit theta -
NYO13_RS09420 (NYO13_09420) 1956534..1956908 + 375 WP_012541261.1 CopC domain-containing protein YobA -
NYO13_RS09425 (NYO13_09425) 1956912..1957781 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
NYO13_RS09430 (NYO13_09430) 1957798..1958136 + 339 WP_008804271.1 YebY family protein -
- 1958258..1958402 - 145 - - Antitoxin
- 1958294..1958396 + 103 - - Toxin
NYO13_RS09435 (NYO13_09435) 1958781..1958924 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
NYO13_RS09440 (NYO13_09440) 1959028..1959996 - 969 WP_163595291.1 VirK/YbjX family protein -
NYO13_RS09445 (NYO13_09445) 1960153..1960806 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
NYO13_RS09450 (NYO13_09450) 1960803..1960994 - 192 WP_002911395.1 YebW family protein -
NYO13_RS09455 (NYO13_09455) 1961092..1961331 - 240 WP_002911393.1 YebV family protein -
NYO13_RS09460 (NYO13_09460) 1961447..1962880 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255019 NZ_CP103419:1958294-1958396 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT255019 NZ_CP103419:c1958402-1958258 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References