Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 66336..66871 Replicon plasmid unnamed2
Accession NZ_CP103403
Organism Pantoea agglomerans strain CHTF15

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NYF24_RS21500 Protein ID WP_172608109.1
Coordinates 66584..66871 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A379LU84
Locus tag NYF24_RS21495 Protein ID WP_022624281.1
Coordinates 66336..66587 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYF24_RS21475 (NYF24_21475) 61939..62208 - 270 WP_010257103.1 DUF1471 family periplasmic protein YahO -
NYF24_RS21480 (NYF24_21480) 62484..63620 - 1137 WP_033786324.1 HlyD family secretion protein -
NYF24_RS21485 (NYF24_21485) 63622..63948 - 327 WP_010257107.1 DUF3302 domain-containing protein -
NYF24_RS21490 (NYF24_21490) 64543..66195 + 1653 WP_228312812.1 intermembrane transport protein PqiB -
NYF24_RS21495 (NYF24_21495) 66336..66587 + 252 WP_022624281.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NYF24_RS21500 (NYF24_21500) 66584..66871 + 288 WP_172608109.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYF24_RS21505 (NYF24_21505) 67141..67431 - 291 WP_022624282.1 XRE family transcriptional regulator -
NYF24_RS21510 (NYF24_21510) 67462..67737 - 276 Protein_60 SAM-dependent DNA methyltransferase -
NYF24_RS21515 (NYF24_21515) 67915..68106 + 192 WP_233267992.1 hypothetical protein -
NYF24_RS21520 (NYF24_21520) 68211..68576 - 366 WP_022624285.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF -
NYF24_RS21525 (NYF24_21525) 68573..68893 - 321 WP_010257131.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE -
NYF24_RS21530 (NYF24_21530) 68893..70560 - 1668 WP_258996230.1 lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase -
NYF24_RS21535 (NYF24_21535) 70560..71462 - 903 WP_258996231.1 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..180424 180424


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11203.11 Da        Isoelectric Point: 10.3856

>T255006 WP_172608109.1 NZ_CP103403:66584-66871 [Pantoea agglomerans]
VSYTVKFREEAFKEWQKLDKSLQQQFAKKLKKCCDNPHIPSARLRGIKDCYKIKLRTSGFRLVYQVIDDQLVIAVVAVGK
RERSDVYHLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9081.35 Da        Isoelectric Point: 3.9507

>AT255006 WP_022624281.1 NZ_CP103403:66336-66587 [Pantoea agglomerans]
MPNIILSDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYCVPAELYEQMLDALDDQELVKLVSERSGQRLLDVDLD
ALL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A379LU84

References