Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 496301..497211 Replicon plasmid unnamed1
Accession NZ_CP103402
Organism Pantoea agglomerans strain CHTF15

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NYF24_RS21135 Protein ID WP_033760865.1
Coordinates 496741..497211 (+) Length 157 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A7X5S5X4
Locus tag NYF24_RS21130 Protein ID WP_033760867.1
Coordinates 496301..496744 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYF24_RS21105 (NYF24_21105) 492518..493423 - 906 WP_258996083.1 alpha/beta hydrolase -
NYF24_RS21110 (NYF24_21110) 493474..494088 - 615 WP_060678871.1 TetR/AcrR family transcriptional regulator -
NYF24_RS21115 (NYF24_21115) 494302..494719 + 418 Protein_482 LysR substrate-binding domain-containing protein -
NYF24_RS21120 (NYF24_21120) 494754..495743 - 990 WP_182504891.1 aldo/keto reductase -
NYF24_RS21125 (NYF24_21125) 495709..495921 - 213 Protein_484 hypothetical protein -
NYF24_RS21130 (NYF24_21130) 496301..496744 + 444 WP_033760867.1 DUF2384 domain-containing protein Antitoxin
NYF24_RS21135 (NYF24_21135) 496741..497211 + 471 WP_033760865.1 RES family NAD+ phosphorylase Toxin
NYF24_RS21140 (NYF24_21140) 497382..498413 + 1032 WP_033760863.1 AI-2E family transporter -
NYF24_RS21145 (NYF24_21145) 498402..501131 - 2730 WP_124890726.1 cation-transporting P-type ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..514938 514938


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre

(16-147)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17480.92 Da        Isoelectric Point: 4.7790

>T255004 WP_033760865.1 NZ_CP103402:496741-497211 [Pantoea agglomerans]
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPEFFRIVQQAEAIPFRFDRRLKPDRK

Download         Length: 471 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16489.88 Da        Isoelectric Point: 9.9250

>AT255004 WP_033760867.1 NZ_CP103402:496301-496744 [Pantoea agglomerans]
MKTFSFSANKTRPPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7X5S5X4

References