Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2081939..2083500 Replicon chromosome
Accession NZ_CP103401
Organism Pantoea agglomerans strain CHTF15

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag NYF24_RS09685 Protein ID WP_258992022.1
Coordinates 2082187..2083500 (+) Length 438 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag NYF24_RS09680 Protein ID WP_010244879.1
Coordinates 2081939..2082187 (+) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYF24_RS09660 (2077186) 2077186..2079411 + 2226 WP_258992019.1 iron ABC transporter permease -
NYF24_RS09665 (2079408) 2079408..2080469 + 1062 WP_258992020.1 ABC transporter ATP-binding protein -
NYF24_RS09670 (2080493) 2080493..2081287 + 795 WP_256849264.1 inositol monophosphatase family protein -
NYF24_RS09675 (2081321) 2081321..2081758 - 438 WP_060680221.1 GNAT family N-acetyltransferase -
NYF24_RS09680 (2081939) 2081939..2082187 + 249 WP_010244879.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
NYF24_RS09685 (2082187) 2082187..2083500 + 1314 WP_258992022.1 type II toxin-antitoxin system HipA family toxin Toxin
NYF24_RS09690 (2083605) 2083605..2083811 + 207 WP_010244885.1 type II toxin-antitoxin system MqsA family antitoxin -
NYF24_RS09695 (2083983) 2083983..2085404 + 1422 WP_258992023.1 M24 family metallopeptidase -
NYF24_RS09700 (2085480) 2085480..2087525 + 2046 WP_010244891.1 FUSC family protein -
NYF24_RS09705 (2087758) 2087758..2088093 - 336 WP_163637049.1 gamma-glutamylcyclotransferase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(149-402)

Antitoxin

(9-54)


Sequences


Toxin        


Download         Length: 438 a.a.        Molecular weight: 49162.79 Da        Isoelectric Point: 8.8383

>T254994 WP_258992022.1 NZ_CP103401:2082187-2083500 [Pantoea agglomerans]
MQRLIAWMNGERVGVLTRQRNGAHEFQYDTGWLSNPLSRPLSLSMPLQVKALTSHAVINFFDNLLPDSPLIRDRIVARYQ
IKSRQPFDLLQEVGRDSVGATMLLLPDMPLPALQARYEVLDETRLESVLSAYQSDIPLGMLREETDFRISVAGAQEKTAL
LLTNEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALARALGIDVPQATIIRAGQMRALAVERFDRRW
SRDKTRLIRLPQEDFCQALGLPSSTKYESDGGPGIAEIMQILMGSSNAIEDRYRFMMFQVFQWLIGATDGHAKNFSLFIE
RGGSYRLTPFYDVISAYPVLGGTGLNKRALKLAMGLRATKGKKTEIDKIFPRHFIATAKSVSFDRDSLQQIFDFFIKAFP
QAVVSVRDALPPDFPQHIADAIFSHSLIMLERLRHKE

Download         Length: 1314 bp


Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9333.58 Da        Isoelectric Point: 5.0775

>AT254994 WP_010244879.1 NZ_CP103401:2081939-2082187 [Pantoea agglomerans]
MIYSPLQLANRLKLIRQRNGWTQSELAKKVGLKQATISHFENAPDSTSLATLFKLLQSLELSLEVQEKEEAGAPQLHDED
EW

Download         Length: 249 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References