254973

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 150516..151063 Replicon plasmid p1
Accession NZ_CP103347
Organism Brucella anthropi strain CGMCC 1.17299

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NW321_RS23500 Protein ID WP_151610665.1
Coordinates 150516..150809 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NW321_RS23505 Protein ID WP_151610664.1
Coordinates 150809..151063 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW321_RS23480 (NW321_23480) 145814..146896 - 1083 WP_151649008.1 FAD-binding oxidoreductase -
NW321_RS23485 (NW321_23485) 146906..147943 - 1038 WP_151610686.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
NW321_RS23490 (NW321_23490) 148069..148986 + 918 WP_151610692.1 LysR family transcriptional regulator -
NW321_RS23495 (NW321_23495) 149633..150346 - 714 WP_259030569.1 IS6 family transposase -
NW321_RS23500 (NW321_23500) 150516..150809 - 294 WP_151610665.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NW321_RS23505 (NW321_23505) 150809..151063 - 255 WP_151610664.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NW321_RS23510 (NW321_23510) 151247..152191 - 945 WP_151610663.1 ornithine cyclodeaminase -
NW321_RS23515 (NW321_23515) 152201..152953 - 753 WP_192799582.1 amino acid ABC transporter ATP-binding protein -
NW321_RS23520 (NW321_23520) 152977..153903 - 927 WP_151610661.1 amino acid ABC transporter permease -
NW321_RS23525 (NW321_23525) 154059..154934 - 876 WP_113534077.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..253576 253576


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11159.93 Da        Isoelectric Point: 6.0740

>T254973 WP_151610665.1 NZ_CP103347:c150809-150516 [Brucella anthropi]
MEFKLSVLAEDDIIAIAEQGIAMFGPVQAKRYHAELFNTLDLIAKNPQMARAREEISPPVRVHPFKAHLIIYQIEADGTV
FVIRVRHAFEDWVRDPF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9471.75 Da        Isoelectric Point: 9.6920

>AT254973 WP_151610664.1 NZ_CP103347:c151063-150809 [Brucella anthropi]
MVTMNVSLPHPMKEWVEAQAKTGRYSNASDYVRDLIRKDQMRSDKIAAMQRFVDEGLQSGPGSRSQDELFAVALANAEKS
LKRN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References