254909

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2968299..2968798 Replicon chromosome
Accession NZ_CP103308
Organism Rhodococcus pyridinivorans strain RL-GZ01

Toxin (Protein)


Gene name relE Uniprot ID H0JMW2
Locus tag NXT08_RS13885 Protein ID WP_006550854.1
Coordinates 2968544..2968798 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NXT08_RS13880 Protein ID WP_019290515.1
Coordinates 2968299..2968547 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXT08_RS13865 (NXT08_13865) 2965380..2966612 - 1233 WP_255024877.1 alpha/beta hydrolase -
NXT08_RS13870 (NXT08_13870) 2966673..2967467 - 795 WP_258912838.1 LLM class F420-dependent oxidoreductase -
NXT08_RS13875 (NXT08_13875) 2967934..2968074 - 141 Protein_2722 hypothetical protein -
NXT08_RS13880 (NXT08_13880) 2968299..2968547 + 249 WP_019290515.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NXT08_RS13885 (NXT08_13885) 2968544..2968798 + 255 WP_006550854.1 Txe/YoeB family addiction module toxin Toxin
NXT08_RS13890 (NXT08_13890) 2968899..2969420 - 522 WP_006550853.1 hypothetical protein -
NXT08_RS13895 (NXT08_13895) 2969577..2970533 + 957 WP_019290518.1 ERCC4 domain-containing protein -
NXT08_RS13900 (NXT08_13900) 2970856..2971089 + 234 WP_258913923.1 transposase -
NXT08_RS13905 (NXT08_13905) 2971096..2971308 + 213 WP_019290520.1 hypothetical protein -
NXT08_RS13910 (NXT08_13910) 2971466..2972092 - 627 WP_006550849.1 TetR family transcriptional regulator -
NXT08_RS13915 (NXT08_13915) 2972195..2973364 + 1170 WP_019290521.1 acyl-CoA dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10064.34 Da        Isoelectric Point: 6.7171

>T254909 WP_006550854.1 NZ_CP103308:2968544-2968798 [Rhodococcus pyridinivorans]
VNITFTDEAWDDYQFWISTDRKQLERVNELVRDCQRDPYSGIGKPERLRHALSGLWSRRIDKEHRLVYEVIDGALVIIAA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9264.55 Da        Isoelectric Point: 6.4661

>AT254909 WP_019290515.1 NZ_CP103308:2968299-2968547 [Rhodococcus pyridinivorans]
MAAITATEARKNFFPLLEQVNKDHTPVEIVSKRGNAVLMSKDDYDAMLETSYLMQSPANARRLLASMQRARGGEHTEREL
IE

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB H0JMW2

Antitoxin

Source ID Structure

References