Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2968299..2968798 Replicon chromosome
Accession NZ_CP103308
Organism Rhodococcus pyridinivorans strain RL-GZ01

Toxin (Protein)


Gene name relE Uniprot ID H0JMW2
Locus tag NXT08_RS13885 Protein ID WP_006550854.1
Coordinates 2968544..2968798 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NXT08_RS13880 Protein ID WP_019290515.1
Coordinates 2968299..2968547 (+) Length 83 a.a.

Genomic Context

NXT08_RS13880NXT08_RS13885NXT08_RS13895NXT08_RS13900NXT08_RS13905NXT08_RS13915NXT08_RS13865NXT08_RS13870NXT08_RS13875NXT08_RS13890NXT08_RS13910
Location: 2968299..2968547 (249 bp)
Type: Antitoxin
Protein ID: WP_019290515.1
Location: 2968544..2968798 (255 bp)
Type: Toxin
Protein ID: WP_006550854.1
Location: 2969577..2970533 (957 bp)
Type: Others
Protein ID: WP_019290518.1
Location: 2970856..2971089 (234 bp)
Type: Others
Protein ID: WP_258913923.1
Location: 2971096..2971308 (213 bp)
Type: Others
Protein ID: WP_019290520.1
Location: 2972195..2973364 (1170 bp)
Type: Others
Protein ID: WP_019290521.1
Location: 2965380..2966612 (1233 bp)
Type: Others
Protein ID: WP_255024877.1
Location: 2966673..2967467 (795 bp)
Type: Others
Protein ID: WP_258912838.1
Location: 2967934..2968074 (141 bp)
Type: Others
Protein ID: Protein_2722
Location: 2968899..2969420 (522 bp)
Type: Others
Protein ID: WP_006550853.1
Location: 2971466..2972092 (627 bp)
Type: Others
Protein ID: WP_006550849.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NXT08_RS13865 (NXT08_13865)2965380..2966612-1233WP_255024877.1alpha/beta hydrolase-
NXT08_RS13870 (NXT08_13870)2966673..2967467-795WP_258912838.1LLM class F420-dependent oxidoreductase-
NXT08_RS13875 (NXT08_13875)2967934..2968074-141Protein_2722hypothetical protein-
NXT08_RS13880 (NXT08_13880)2968299..2968547+249WP_019290515.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
NXT08_RS13885 (NXT08_13885)2968544..2968798+255WP_006550854.1Txe/YoeB family addiction module toxinToxin
NXT08_RS13890 (NXT08_13890)2968899..2969420-522WP_006550853.1hypothetical protein-
NXT08_RS13895 (NXT08_13895)2969577..2970533+957WP_019290518.1ERCC4 domain-containing protein-
NXT08_RS13900 (NXT08_13900)2970856..2971089+234WP_258913923.1transposase-
NXT08_RS13905 (NXT08_13905)2971096..2971308+213WP_019290520.1hypothetical protein-
NXT08_RS13910 (NXT08_13910)2971466..2972092-627WP_006550849.1TetR family transcriptional regulator-
NXT08_RS13915 (NXT08_13915)2972195..2973364+1170WP_019290521.1acyl-CoA dehydrogenase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10064.34 Da        Isoelectric Point: 6.7171

>T254909 WP_006550854.1 NZ_CP103308:2968544-2968798 [Rhodococcus pyridinivorans]
VNITFTDEAWDDYQFWISTDRKQLERVNELVRDCQRDPYSGIGKPERLRHALSGLWSRRIDKEHRLVYEVIDGALVIIAA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9264.55 Da        Isoelectric Point: 6.4661

>AT254909 WP_019290515.1 NZ_CP103308:2968299-2968547 [Rhodococcus pyridinivorans]
MAAITATEARKNFFPLLEQVNKDHTPVEIVSKRGNAVLMSKDDYDAMLETSYLMQSPANARRLLASMQRARGGEHTEREL
IE

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBH0JMW2

Antitoxin

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Source
ID
Structure
No matching records found

References