254908

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2253343..2253902 Replicon chromosome
Accession NZ_CP103308
Organism Rhodococcus pyridinivorans strain RL-GZ01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NXT08_RS10445 Protein ID WP_024102981.1
Coordinates 2253343..2253621 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NXT08_RS10450 Protein ID WP_024102980.1
Coordinates 2253618..2253902 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXT08_RS10415 (NXT08_10415) 2248464..2249183 + 720 WP_258913842.1 2OG-Fe(II) oxygenase -
NXT08_RS10420 (NXT08_10420) 2249220..2250191 - 972 WP_006551850.1 phosphotriesterase -
NXT08_RS10425 (NXT08_10425) 2250236..2251066 - 831 WP_024102985.1 SDR family oxidoreductase -
NXT08_RS10430 (NXT08_10430) 2251187..2251849 + 663 WP_024102984.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
NXT08_RS10435 (NXT08_10435) 2251999..2252748 + 750 WP_024102983.1 cutinase family protein -
NXT08_RS10440 (NXT08_10440) 2252807..2253286 + 480 WP_024102982.1 MarR family transcriptional regulator -
NXT08_RS10445 (NXT08_10445) 2253343..2253621 - 279 WP_024102981.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NXT08_RS10450 (NXT08_10450) 2253618..2253902 - 285 WP_024102980.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NXT08_RS10455 (NXT08_10455) 2254122..2254940 - 819 WP_006551857.1 family 1 encapsulin nanocompartment shell protein -
NXT08_RS10460 (NXT08_10460) 2254937..2255965 - 1029 WP_024102977.1 Dyp-type peroxidase -
NXT08_RS10465 (NXT08_10465) 2256042..2257643 - 1602 WP_252173680.1 L-lactate permease -
NXT08_RS10470 (NXT08_10470) 2257648..2258076 - 429 WP_258913843.1 HIT family protein -
NXT08_RS10475 (NXT08_10475) 2258073..2258699 - 627 WP_231911981.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(34-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10268.82 Da        Isoelectric Point: 10.2002

>T254908 WP_024102981.1 NZ_CP103308:c2253621-2253343 [Rhodococcus pyridinivorans]
MSTPDHPYRLVMARSAARAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR

Download         Length: 279 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10494.56 Da        Isoelectric Point: 4.2336

>AT254908 WP_024102980.1 NZ_CP103308:c2253902-2253618 [Rhodococcus pyridinivorans]
MTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVDVQ
ELTQLMRDARSSEE

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References