Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 289326..290278 Replicon chromosome
Accession NZ_CP103308
Organism Rhodococcus pyridinivorans strain RL-GZ01

Toxin (Protein)


Gene name pezT Uniprot ID H0JT30
Locus tag NXT08_RS01385 Protein ID WP_006552790.1
Coordinates 289709..290278 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID A0A7M2XIK8
Locus tag NXT08_RS01380 Protein ID WP_016696422.1
Coordinates 289326..289712 (+) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXT08_RS01360 (NXT08_01360) 285040..285972 + 933 WP_258913393.1 TAXI family TRAP transporter solute-binding subunit -
NXT08_RS01365 (NXT08_01365) 287095..287430 + 336 WP_258913394.1 hypothetical protein -
NXT08_RS01370 (NXT08_01370) 287612..287977 - 366 WP_024101068.1 HNH endonuclease -
NXT08_RS01375 (NXT08_01375) 288047..289117 - 1071 WP_019289578.1 methyltransferase domain-containing protein -
NXT08_RS01380 (NXT08_01380) 289326..289712 + 387 WP_016696422.1 hypothetical protein Antitoxin
NXT08_RS01385 (NXT08_01385) 289709..290278 + 570 WP_006552790.1 zeta toxin family protein Toxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(4-136)

Antitoxin

ParD-like antitoxin of type II bacterial toxin-antitoxin system

(7-104)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 20552.71 Da        Isoelectric Point: 10.6895

>T254907 WP_006552790.1 NZ_CP103308:289709-290278 [Rhodococcus pyridinivorans]
MRRLDLIVGPNGSGKSTFVELSLAPLLPRSVFVNADVIARQRWPDRAEEMSYEAAQLAAAARDRLLRQGRSFIAETVFSH
PSKLELIDRAHEVGFTVVLHVMLVPEAMSVLRVQHRVASGGHAVPEDKIRARYRRLWPLVTEAIGRADQASVYDTASGTP
VVVARFAGGVPVGAVRWPGWAPAALTGLG

Download         Length: 570 bp

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14038.49 Da        Isoelectric Point: 4.7096

>AT254907 WP_016696422.1 NZ_CP103308:289326-289712 [Rhodococcus pyridinivorans]
MTSSTDKVTRFDAELVDSAIAEGGRQNRTGRQQLEYWARIGRAMTAHETASLHRVHEALAGTRELSELTAAEGRLFDAEI
DARLADGLARTDYAEVLAARGVTTVVLDDEGRLVEQRPDGSRRVLDDA

Download         Length: 387 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T7RLW6

Antitoxin

Source ID Structure
AlphaFold DB A0A7M2XIK8

References