Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
Location | 3654455..3655963 | Replicon | chromosome |
Accession | NZ_CP103307 | ||
Organism | Pseudomonas aeruginosa strain PLL01 |
Toxin (Protein)
Gene name | - | Uniprot ID | Q9HYX1 |
Locus tag | NX763_RS16975 | Protein ID | WP_003119682.1 |
Coordinates | 3655376..3655963 (-) | Length | 196 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | Q9HYX2 |
Locus tag | NX763_RS16970 | Protein ID | WP_003115566.1 |
Coordinates | 3654455..3655309 (-) | Length | 285 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NX763_RS16955 (NX763_16955) | 3649874..3650083 | + | 210 | WP_003115568.1 | cold-shock protein | - |
NX763_RS16960 (NX763_16960) | 3650144..3652018 | - | 1875 | WP_003091605.1 | MFS transporter | - |
NX763_RS16965 (NX763_16965) | 3652193..3654358 | - | 2166 | WP_003115567.1 | TonB-dependent receptor family protein | - |
NX763_RS16970 (NX763_16970) | 3654455..3655309 | - | 855 | WP_003115566.1 | AraC family transcriptional regulator | Antitoxin |
NX763_RS16975 (NX763_16975) | 3655376..3655963 | - | 588 | WP_003119682.1 | GNAT family protein | Toxin |
NX763_RS16980 (NX763_16980) | 3656229..3659708 | + | 3480 | WP_003114080.1 | PAS domain-containing hybrid sensor histidine kinase/response regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 196 a.a. Molecular weight: 21901.23 Da Isoelectric Point: 9.8676
>T254904 WP_003119682.1 NZ_CP103307:c3655963-3655376 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
Download Length: 588 bp
Antitoxin
Download Length: 285 a.a. Molecular weight: 31933.23 Da Isoelectric Point: 7.3276
>AT254904 WP_003115566.1 NZ_CP103307:c3655309-3654455 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHADSLETQTRWRETVLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTIYE
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHADSLETQTRWRETVLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTIYE
Download Length: 855 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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