Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 5989000..5989760 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag NX720_RS24345 Protein ID WP_262598148.1
Coordinates 5989000..5989506 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag NX720_RS24350 Protein ID WP_262598150.1
Coordinates 5989497..5989760 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS24335 (NX720_24335) 5984286..5986190 + 1905 WP_262598144.1 TrbC family F-type conjugative pilus assembly protein -
NX720_RS24340 (NX720_24340) 5986163..5989009 + 2847 WP_262598145.1 conjugal transfer protein TraN -
NX720_RS24345 (NX720_24345) 5989000..5989506 - 507 WP_262598148.1 GNAT family N-acetyltransferase Toxin
NX720_RS24350 (NX720_24350) 5989497..5989760 - 264 WP_262598150.1 DUF1778 domain-containing protein Antitoxin
NX720_RS24355 (NX720_24355) 5989839..5990120 + 282 WP_262598152.1 type IV conjugative transfer system protein TraL -
NX720_RS24360 (NX720_24360) 5990117..5990671 + 555 WP_262598155.1 type IV conjugative transfer system protein TraE -
NX720_RS24365 (NX720_24365) 5990692..5990841 + 150 WP_262598156.1 hypothetical protein -
NX720_RS24370 (NX720_24370) 5990918..5991538 + 621 WP_262598158.1 hypothetical protein -
NX720_RS24375 (NX720_24375) 5991535..5991663 + 129 WP_262598159.1 hypothetical protein -
NX720_RS24380 (NX720_24380) 5992050..5992835 + 786 WP_262598161.1 type-F conjugative transfer system secretin TraK -
NX720_RS24385 (NX720_24385) 5992858..5994033 + 1176 WP_262598162.1 TraB/VirB10 family protein -
NX720_RS24390 (NX720_24390) 5994030..5994473 + 444 WP_262598164.1 TraV family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 5967195..6000983 33788


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(25-146)

Antitoxin

Vibrio phage ICP1, Orf50

(3-87)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18636.61 Da        Isoelectric Point: 8.5010

>T254900 WP_262598148.1 NZ_CP103300:c5989506-5989000 [Endozoicomonas euniceicola]
VGVIRAPELLTKDHNTDDFDCGHDVLTEWLKKTALKNQSANASRTFVVCKGDRVVGYYALSSGSIERMQTPKSLARNMPD
PIPVTVLGRLAIDQEHQGMRIGSGLLKDAMMRTLVVSQHIGVKAMLVHAVSEEARQFYLQYGFKESPFNPMTLMLPVKHI
VGLFPDQG

Download         Length: 507 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9640.23 Da        Isoelectric Point: 4.4155

>AT254900 WP_262598150.1 NZ_CP103300:c5989760-5989497 [Endozoicomonas euniceicola]
MAKTVPINMRVEPVQQALLTMAAAVLNKDRTAFILDVACREAMNVLLDQRVFTLDEAQTKAFEEALEAPVPEQSKLSKLL
AEAAPWE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References