254898

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 5168542..5169133 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NX720_RS20950 Protein ID WP_262597236.1
Coordinates 5168542..5168847 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NX720_RS20955 Protein ID WP_262597237.1
Coordinates 5168840..5169133 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS20920 (NX720_20920) 5164656..5165087 + 432 Protein_4081 transposase -
NX720_RS20925 (NX720_20925) 5165272..5166108 + 837 WP_262597230.1 transposase -
NX720_RS20930 (NX720_20930) 5166146..5167639 + 1494 WP_262596131.1 ISKra4 family transposase -
NX720_RS20935 (NX720_20935) 5167650..5167850 + 201 Protein_4084 hypothetical protein -
NX720_RS20940 (NX720_20940) 5167861..5168061 + 201 WP_262597232.1 type II toxin-antitoxin system RelE/ParE family toxin -
NX720_RS20945 (NX720_20945) 5168039..5168338 + 300 WP_262597234.1 helix-turn-helix transcriptional regulator -
NX720_RS20950 (NX720_20950) 5168542..5168847 + 306 WP_262597236.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NX720_RS20955 (NX720_20955) 5168840..5169133 + 294 WP_262597237.1 putative addiction module antidote protein Antitoxin
NX720_RS20960 (NX720_20960) 5169375..5169626 - 252 WP_262597238.1 hypothetical protein -
NX720_RS20965 (NX720_20965) 5169728..5170639 - 912 WP_262597240.1 hypothetical protein -
NX720_RS20970 (NX720_20970) 5170894..5172603 + 1710 WP_262597242.1 hypothetical protein -
NX720_RS20975 (NX720_20975) 5172603..5173307 + 705 WP_262597244.1 OmpA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5160894..5170639 9745


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(40-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-89)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11776.80 Da        Isoelectric Point: 10.5545

>T254898 WP_262597236.1 NZ_CP103300:5168542-5168847 [Endozoicomonas euniceicola]
MITIKQHDTFRQWLKAVKDPKAKSLILSRIKRMAFGLFGDVKPVGGGFSELRIDTGKGYRVYFMRQGDELIILLCGSQKK
NQQKQIELAKTLYKEWRNENE

Download         Length: 306 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10263.51 Da        Isoelectric Point: 4.5679

>AT254898 WP_262597237.1 NZ_CP103300:5168840-5169133 [Endozoicomonas euniceicola]
MNEKLTDFDPAEYLDDDESIQHYIDEAVATGHAGFIADSLGVVARAKGMTALAKATDLSRESLYRSLSGEGNPNLKTLLA
VCSALGVTLHIGKPAQS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References