Detailed information of TA system TA254894

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 3162660..3164076
• Replicon: chromosome
• Accession: NZ_CP103300
• Organism: Endozoicomonas euniceicola strain EF212

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: NX720_RS12505
• Protein ID: WP_262601435.1
• Coordinates: 3162660..3163550 (-)
• Length: 297 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: NX720_RS12510
• Protein ID: WP_262601436.1
• Coordinates: 3163552..3164076 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NX720_RS12495 (NX720_12495)	3157743..3158663	+	921	WP_262601433.1	type I-E CRISPR-associated endonuclease Cas1e	-
NX720_RS12500 (NX720_12500)	3158666..3158953	+	288	WP_262601434.1	type I-E CRISPR-associated endoribonuclease Cas2e	-
NX720_RS12505 (NX720_12505)	3162660..3163550	-	891	WP_262601435.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
NX720_RS12510 (NX720_12510)	3163552..3164076	-	525	WP_262601436.1	hypothetical protein	Antitoxin
NX720_RS12515 (NX720_12515)	3164301..3164723	-	423	WP_262600864.1	IS200/IS605 family transposase	-
NX720_RS12520 (NX720_12520)	3164770..3165696	+	927	WP_262601437.1	transposase	-
NX720_RS12525 (NX720_12525)	3165713..3166477	-	765	WP_262601438.1	NRDE family protein	-
NX720_RS12530 (NX720_12530)	3166560..3167354	+	795	WP_262601439.1	carbon-nitrogen hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (40-270)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 297 a.a.
• Molecular weight: 34175.26 Da
• Isoelectric Point: 7.1084

>T254894 WP_262601435.1 NZ_CP103300:c3163550-3162660 [Endozoicomonas euniceicola]
MLKEQIRNIVASNPEYAAITPVIEKEILHHDVIHVLIREGVMQPLTFIGGTSLRMCYNSSRLSEDLDFNGGHGFKPSDFD
GLEVEIEKYIQNKYETKVWVSKPDENRQGNTSSWKISIEKEACRPDLPRQKMHIDICAIPSIDTRKKPLTNHYNIVVPTE
GLLVPVQSLEETLADKFIALAYRSRRIKPRDVWDIVWIRQKGIDLSTSLIEKKLEARNKTKAEFTEALHTQITKLLKDNE
VRTDFNAEMTRFIPESIKQRTLDNPEYWAYVQAEIQIMATPLLKASQPRNPFDMSL

Nucleotide

• Length: 891 bp

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19258.40 Da
• Isoelectric Point: 10.2096

>AT254894 WP_262601436.1 NZ_CP103300:c3164076-3163552 [Endozoicomonas euniceicola]
MTKKDKLLMVLSEAVKAGGGIHTAAEIAYMIGEKHSATFTKFLAVYAKKGLIRRVATGLFESTLTPPDPTTAIYKIAKKL
RSDVISYISLESQLSYTGDISQIPMGRLTIITKGRNGTFSTPYGVIEFTHTKKAIDRIAPNLYFDETAGIYRAKTSQAIA
DLKDCKRNRHMLDH

Nucleotide

• Length: 525 bp