254892

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2955844..2956654 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag NX720_RS11520 Protein ID WP_262601254.1
Coordinates 2956244..2956654 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag NX720_RS11515 Protein ID WP_262601253.1
Coordinates 2955844..2956251 (+) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS11485 (NX720_11485) 2951264..2951542 + 279 WP_262601247.1 helix-turn-helix transcriptional regulator -
NX720_RS11490 (NX720_11490) 2951539..2952816 + 1278 WP_262601248.1 type II toxin-antitoxin system HipA family toxin -
NX720_RS11495 (NX720_11495) 2952979..2953290 + 312 WP_262601249.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
NX720_RS11500 (NX720_11500) 2953597..2953839 + 243 WP_262601250.1 helix-turn-helix transcriptional regulator -
NX720_RS11505 (NX720_11505) 2953836..2955077 + 1242 WP_262601251.1 type II toxin-antitoxin system HipA family toxin -
NX720_RS11510 (NX720_11510) 2955128..2955700 - 573 WP_262601252.1 hypothetical protein -
NX720_RS11515 (NX720_11515) 2955844..2956251 + 408 WP_262601253.1 nucleotidyltransferase domain-containing protein Antitoxin
NX720_RS11520 (NX720_11520) 2956244..2956654 + 411 WP_262601254.1 DUF86 domain-containing protein Toxin
NX720_RS11525 (NX720_11525) 2956896..2957183 + 288 WP_262601255.1 putative addiction module antidote protein -
NX720_RS11530 (NX720_11530) 2957384..2957626 + 243 WP_262601256.1 helix-turn-helix transcriptional regulator -
NX720_RS11535 (NX720_11535) 2957623..2958864 + 1242 WP_262601257.1 type II toxin-antitoxin system HipA family toxin -
NX720_RS11540 (NX720_11540) 2959014..2959262 + 249 WP_262601258.1 hypothetical protein -
NX720_RS11545 (NX720_11545) 2959857..2960939 + 1083 WP_262601259.1 Fic family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(15-129)

Antitoxin

Polymerase beta, nucleotidyltransferase

(10-100)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15774.18 Da        Isoelectric Point: 6.0900

>T254892 WP_262601254.1 NZ_CP103300:2956244-2956654 [Endozoicomonas euniceicola]
MDDVILNKYAIIQRCLMRIREEYVGHENELTTNFTRQDSIILNIQRASQAALDLSNRIIRLKQLPVPQESRESFSILSDH
SLVSTTLTDSMMKMVGFRNIAVHEYQKLNLDILKAVIEQHVQDIERFAVEVMKSVD

Download         Length: 411 bp

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 15439.67 Da        Isoelectric Point: 6.7050

>AT254892 WP_262601253.1 NZ_CP103300:2955844-2956251 [Endozoicomonas euniceicola]
MLPKTTCSHIIQYLKSEFKESLQGIVLYGSQAAGKATERSDIDLAVLLNRNISQYPLWNTAQTLACQLKKDVDLISLRKA
TTVLQKEVVEHGNWLLKSDEFACNLFETHVFSQYQQLQEDRREIIDDLIGRIKNG

Download         Length: 408 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References