Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2279553..2280199 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NX720_RS08690 Protein ID WP_262601556.1
Coordinates 2279792..2280199 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NX720_RS08685 Protein ID WP_262600739.1
Coordinates 2279553..2279792 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS08665 (NX720_08665) 2275449..2276474 + 1026 WP_262600736.1 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase -
NX720_RS08670 (NX720_08670) 2276547..2277032 + 486 WP_262600737.1 hypothetical protein -
NX720_RS08675 (NX720_08675) 2277118..2278239 + 1122 WP_262601555.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
NX720_RS08680 (NX720_08680) 2278465..2279385 - 921 WP_262600738.1 metallophosphoesterase -
NX720_RS08685 (NX720_08685) 2279553..2279792 + 240 WP_262600739.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NX720_RS08690 (NX720_08690) 2279792..2280199 + 408 WP_262601556.1 type II toxin-antitoxin system VapC family toxin Toxin
NX720_RS08695 (NX720_08695) 2280225..2281871 - 1647 WP_262600740.1 dihydrolipoyllysine-residue acetyltransferase -
NX720_RS08700 (NX720_08700) 2281931..2284588 - 2658 WP_262600741.1 pyruvate dehydrogenase (acetyl-transferring), homodimeric type -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-125)

Antitoxin

SpoVT-AbrB domain

(9-53)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15146.10 Da        Isoelectric Point: 6.3329

>T254891 WP_262601556.1 NZ_CP103300:2279792-2280199 [Endozoicomonas euniceicola]
ILKFMLDTDISIFVLRHRSPELLGVFNAYDGQIAISSITLSELLHGVEKSSDPKQNRNTVESFVSRLEVLDYTSKASAHY
GDIRANLERRGQIIGVNDIHIAAHARSEGLIAVTNNVREFSRVDGLRVENWLEQA

Download         Length: 408 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9246.32 Da        Isoelectric Point: 8.8327

>AT254891 WP_262600739.1 NZ_CP103300:2279553-2279792 [Endozoicomonas euniceicola]
MAQGTVFENNRTQAVRLPAETRFPDNIKKVRVRVRGQDRILSPIGKTWDSFFNVTPENSVTDDFMTERASQEQKEREQF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References