254890

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/couple_hipB(antitoxin)
Location 1588417..1589006 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag NX720_RS06155 Protein ID WP_262600101.1
Coordinates 1588417..1588581 (+) Length 55 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag NX720_RS06160 Protein ID WP_262600103.1
Coordinates 1588578..1589006 (+) Length 143 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS06125 (NX720_06125) 1584536..1584805 + 270 WP_262600096.1 hypothetical protein -
NX720_RS06130 (NX720_06130) 1584771..1585082 + 312 WP_262601537.1 HipA domain-containing protein -
NX720_RS06135 (NX720_06135) 1585057..1585302 - 246 Protein_1203 IS200/IS605 family transposase -
NX720_RS06140 (NX720_06140) 1585455..1586882 + 1428 WP_262600098.1 hypothetical protein -
NX720_RS06145 (NX720_06145) 1586909..1587103 - 195 Protein_1205 transposase -
NX720_RS06150 (NX720_06150) 1587169..1588341 + 1173 WP_262600099.1 transposase -
NX720_RS06155 (NX720_06155) 1588417..1588581 + 165 WP_262600101.1 hypothetical protein Toxin
NX720_RS06160 (NX720_06160) 1588578..1589006 + 429 WP_262600103.1 helix-turn-helix transcriptional regulator Antitoxin
NX720_RS06165 (NX720_06165) 1589040..1589750 - 711 WP_262600105.1 DUF3581 domain-containing protein -
NX720_RS06170 (NX720_06170) 1590068..1591000 + 933 WP_262600107.1 hypothetical protein -
NX720_RS06175 (NX720_06175) 1591149..1592087 + 939 WP_262600109.1 hypothetical protein -
NX720_RS06180 (NX720_06180) 1592095..1593120 - 1026 WP_262600110.1 lipoyl synthase -
NX720_RS06185 (NX720_06185) 1593154..1593840 - 687 WP_262600112.1 lipoyl(octanoyl) transferase LipB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(78-116)


Sequences

Toxin        


Download         Length: 55 a.a.        Molecular weight: 5947.91 Da        Isoelectric Point: 4.4911

>T254890 WP_262600101.1 NZ_CP103300:1588417-1588581 [Endozoicomonas euniceicola]
VTADSVIEELSRLATQLVDLKPRLADQGVPESIVNLPAIGFGFLNDKLKKWDLI

Download         Length: 165 bp

Antitoxin


Download         Length: 143 a.a.        Molecular weight: 15507.80 Da        Isoelectric Point: 10.9924

>AT254890 WP_262600103.1 NZ_CP103300:1588578-1589006 [Endozoicomonas euniceicola]
MNTKMTSNARDRLARLRAQKSQQQLQKTAGNTSVSKPGSAPGSREAMILELMVQVLKGDITDGQLLQQLRKQLLGLNQDR
FAELVGVSRKTVSDIERGKGSPSQQVLNDVFKPFGLRAGIIPVSQSQTEKLINKAHDELLGG

Download         Length: 429 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References