Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 1390856..1391655 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NX720_RS05410 Protein ID WP_262568568.1
Coordinates 1391122..1391655 (+) Length 178 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NX720_RS05405 Protein ID WP_262599912.1
Coordinates 1390856..1391125 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS05380 (NX720_05380) 1386150..1386920 + 771 WP_262599905.1 hypothetical protein -
NX720_RS05385 (NX720_05385) 1387012..1387347 - 336 WP_262599907.1 group II intron maturase-specific domain-containing protein -
NX720_RS05390 (NX720_05390) 1387466..1388713 - 1248 WP_262599908.1 group II intron reverse transcriptase/maturase -
NX720_RS05395 (NX720_05395) 1388820..1388948 - 129 WP_262599910.1 hypothetical protein -
NX720_RS05400 (NX720_05400) 1389244..1389954 - 711 WP_262599911.1 group II intron reverse transcriptase/maturase -
NX720_RS05405 (NX720_05405) 1390856..1391125 + 270 WP_262599912.1 DUF1778 domain-containing protein Antitoxin
NX720_RS05410 (NX720_05410) 1391122..1391655 + 534 WP_262568568.1 GNAT family N-acetyltransferase Toxin
NX720_RS05415 (NX720_05415) 1392090..1392359 - 270 Protein_1059 transposase -
NX720_RS05420 (NX720_05420) 1392847..1394259 - 1413 WP_262599914.1 transposase -
NX720_RS05425 (NX720_05425) 1394402..1395568 + 1167 WP_262599916.1 ISAs1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(96-155)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 19927.37 Da        Isoelectric Point: 8.4877

>T254889 WP_262568568.1 NZ_CP103300:1391122-1391655 [Endozoicomonas euniceicola]
VSWSKEFVELDKGIHDRASFDCGEAELNLFIQTQAAKHMQAGISRTMVLPASSPLPNQKIPVCAFYSIVPSSICRDTLPK
ALAKKLPRYPIPVFLIAQLAVHREFHGEGLGKICLINALKYLWEINSHMRAYAIIVDCLTDSAERFYAKYGFEVLCEHNG
RVRMFLPMKTVAQLFGP

Download         Length: 534 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9954.35 Da        Isoelectric Point: 4.3813

>AT254889 WP_262599912.1 NZ_CP103300:1390856-1391125 [Endozoicomonas euniceicola]
MATARLDLRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVISEYESITVENDVFDRFTEACEKAKVPNKALLDAL
AFTEEKGVK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References