254888

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1027159..1028873 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag NX720_RS03975 Protein ID WP_262599549.1
Coordinates 1028229..1028873 (-) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag NX720_RS03970 Protein ID WP_262599547.1
Coordinates 1027159..1028232 (-) Length 358 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS03935 (NX720_03935) 1022554..1022731 + 178 Protein_767 IS1 family transposase -
NX720_RS03940 (NX720_03940) 1023181..1023531 - 351 WP_262599543.1 DUF805 domain-containing protein -
NX720_RS03945 (NX720_03945) 1024156..1024581 + 426 Protein_769 sel1 repeat family protein -
NX720_RS03950 (NX720_03950) 1024564..1025121 + 558 Protein_770 sel1 repeat family protein -
NX720_RS03955 (NX720_03955) 1025146..1025769 + 624 Protein_771 sel1 repeat family protein -
NX720_RS03960 (NX720_03960) 1025797..1026372 + 576 Protein_772 sel1 repeat family protein -
NX720_RS03965 (NX720_03965) 1026703..1027023 + 321 WP_262599545.1 Rap1a/Tai family immunity protein -
NX720_RS03970 (NX720_03970) 1027159..1028232 - 1074 WP_262599547.1 macro domain-containing protein Antitoxin
NX720_RS03975 (NX720_03975) 1028229..1028873 - 645 WP_262599549.1 DUF4433 domain-containing protein Toxin
NX720_RS03980 (NX720_03980) 1028873..1029097 - 225 WP_262599550.1 hypothetical protein -
NX720_RS03985 (NX720_03985) 1029094..1030383 - 1290 WP_262599551.1 restriction endonuclease subunit S -
NX720_RS03990 (NX720_03990) 1030376..1033081 - 2706 WP_262599552.1 N-6 DNA methylase -
NX720_RS03995 (NX720_03995) 1033274..1033678 - 405 WP_262599553.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 25149.69 Da        Isoelectric Point: 6.4910

>T254888 WP_262599549.1 NZ_CP103300:c1028873-1028229 [Endozoicomonas euniceicola]
MFYKNLNPQKALIWRITHRNNLPWLLDNGLHCGTSTVRSSDWVDIGNPELIDKRGNHPVPDKPGGVLNDYVPFYFTPFSV
MMQNIHTGWSVPKRDNDEIVILVSSLYRIRELELPFLFTDSHAYYMWANFYSGLADLDKVDWSILQRRDFKRDQDDPAKF
ERYQAEALVYRHVPVEALLGVVCYTEELKLQIDQLMQQRGLGLSVYVRTGWYFQ

Download         Length: 645 bp

Antitoxin


Download         Length: 358 a.a.        Molecular weight: 40583.11 Da        Isoelectric Point: 8.5671

>AT254888 WP_262599547.1 NZ_CP103300:c1028232-1027159 [Endozoicomonas euniceicola]
MIKYTTGNLLDAPAEALVNTVNTVGVMGKGIALMFKERFDKNMKEYVKACKAKEVQVGKMFVTKTDELIGPHWVVNFPTK
KHWRYPSKMEWVVDGLQDLKRFILEENVRSIAIPPLGAGNGGLPWPAVREQIELALSDLHDVEILIFEPTAKYQNIAKSK
GAEKLTPARALIAELIRRYWVPGMECSLLEVQKLAWVLERVIEKQQLENPLQLQFSPENYGPYANRLQHVLNHLDGSYLK
SDKRIADSSPLDVIRFNEKYKIKLQTYLESKATKYLPALEEASKIISGFESPFGLELLTTVDWLISRESCNGTVDDVMEA
IKQWPAGSKWASRKEKLFSERDVSIALSRLQEMKMAA

Download         Length: 1074 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References