Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 635645..636318 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag NX720_RS02425 Protein ID WP_262599156.1
Coordinates 635965..636318 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag NX720_RS02420 Protein ID WP_262568332.1
Coordinates 635645..635968 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS02390 (NX720_02390) 630683..632665 - 1983 WP_262599151.1 hypothetical protein -
NX720_RS02395 (NX720_02395) 632964..633488 - 525 WP_262599152.1 crossover junction endodeoxyribonuclease RuvC -
NX720_RS02400 (NX720_02400) 633630..633758 + 129 WP_262599154.1 hypothetical protein -
NX720_RS02405 (NX720_02405) 633829..634257 - 429 WP_262595354.1 IS200/IS605 family transposase -
NX720_RS02410 (NX720_02410) 634323..635201 + 879 WP_262599155.1 transposase -
NX720_RS02415 (NX720_02415) 635211..635495 + 285 WP_262601704.1 transposase -
NX720_RS02420 (NX720_02420) 635645..635968 - 324 WP_262568332.1 XRE family transcriptional regulator Antitoxin
NX720_RS02425 (NX720_02425) 635965..636318 - 354 WP_262599156.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NX720_RS02430 (NX720_02430) 636565..636879 - 315 WP_262599157.1 type II toxin-antitoxin system RelE/ParE family toxin -
NX720_RS02435 (NX720_02435) 636857..637117 - 261 WP_262599158.1 type II toxin-antitoxin system ParD family antitoxin -
NX720_RS02440 (NX720_02440) 637316..639544 - 2229 WP_262599159.1 TonB-dependent hemoglobin/transferrin/lactoferrin family receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 633829..634257 428


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-104)

Antitoxin

HigA2-like, helix-turn-helix domain

(16-106)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13435.37 Da        Isoelectric Point: 10.1648

>T254887 WP_262599156.1 NZ_CP103300:c636318-635965 [Endozoicomonas euniceicola]
MSNEKPIKWMGSALDDLLQFPDPAKREAGYQLSRIQNDLEPEHWKDFKMVGAGAKGIIISEDGDAFRVMYVAKFEEAVYV
LHSFQKKTQQTSKQDKQIASRRYKQVVAERSKKRKGG

Download         Length: 354 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11876.96 Da        Isoelectric Point: 10.3656

>AT254887 WP_262568332.1 NZ_CP103300:c635968-635645 [Endozoicomonas euniceicola]
MSKRIIGHTTPTGGNVFSDLGFSPEEAEKLKADSDLKIKADLKIQLMTEITKTIQERHLKQEEAALLMNVNRPRVSDVMT
GKASKFTIDALVVMLQRLGRSVILKIA

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References