Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | spoIISABC/SpoIISA-SpoIISB |
Location | 341640..342556 | Replicon | chromosome |
Accession | NZ_CP103290 | ||
Organism | Bacillus atrophaeus strain NS2 |
Toxin (Protein)
Gene name | spoIISA | Uniprot ID | - |
Locus tag | NXY85_RS01860 | Protein ID | WP_258729068.1 |
Coordinates | 341810..342556 (-) | Length | 249 a.a. |
Antitoxin (Protein)
Gene name | spoIISB | Uniprot ID | A0A837Y0B4 |
Locus tag | NXY85_RS01855 | Protein ID | WP_010788357.1 |
Coordinates | 341640..341810 (-) | Length | 57 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NXY85_RS01820 | 338396..338725 | + | 330 | WP_258729065.1 | XkdW family protein | - |
NXY85_RS01825 | 338722..338886 | + | 165 | WP_061571316.1 | XkdX family protein | - |
NXY85_RS01830 | 338962..339810 | + | 849 | WP_258729066.1 | phage portal protein | - |
NXY85_RS01835 | 339884..340162 | + | 279 | WP_003327427.1 | hemolysin XhlA family protein | - |
NXY85_RS01840 | 340175..340438 | + | 264 | WP_003327426.1 | phage holin | - |
NXY85_RS01845 | 340451..341344 | + | 894 | WP_003327425.1 | N-acetylmuramoyl-L-alanine amidase | - |
NXY85_RS01850 | 341420..341542 | - | 123 | WP_010788356.1 | hypothetical protein | - |
NXY85_RS01855 | 341640..341810 | - | 171 | WP_010788357.1 | three component toxin-antitoxin-antitoxin system antitoxin SpoIISB | Antitoxin |
NXY85_RS01860 | 341810..342556 | - | 747 | WP_258729068.1 | type II toxin-antitoxin system SpoIISA family toxin | Toxin |
NXY85_RS01865 | 342665..343663 | - | 999 | WP_003327422.1 | inorganic phosphate transporter | - |
NXY85_RS01870 | 343676..344293 | - | 618 | WP_003327421.1 | DUF47 domain-containing protein | - |
NXY85_RS01875 | 344581..345897 | - | 1317 | WP_258729069.1 | amino acid permease | - |
NXY85_RS01880 | 346317..347267 | + | 951 | WP_258729070.1 | ring-cleaving dioxygenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 306685..363374 | 56689 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 29096.63 Da Isoelectric Point: 4.5650
>T254856 WP_258729068.1 NZ_CP103290:c342556-341810 [Bacillus atrophaeus]
MLLFFQIMVWCIMAALGLYVYAVWRFEAKVKEKMFAIRKTWYLIFVIGAMVYWTYDPSSLFREWTNYLIVAVSFALVDAF
IFLSAYVKKLAGNELETDTREILEENNEMLHVYLDKLKTYQYLLKNEPIHVYYGSIEAYAEGIDKLLKTYADKMNLTASL
CEYSTQLEKDRLTEHMDDAFEVQSRLDRKDVYYDQHGKLALIPFTVQTRSYVIKLASDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGDG
MLLFFQIMVWCIMAALGLYVYAVWRFEAKVKEKMFAIRKTWYLIFVIGAMVYWTYDPSSLFREWTNYLIVAVSFALVDAF
IFLSAYVKKLAGNELETDTREILEENNEMLHVYLDKLKTYQYLLKNEPIHVYYGSIEAYAEGIDKLLKTYADKMNLTASL
CEYSTQLEKDRLTEHMDDAFEVQSRLDRKDVYYDQHGKLALIPFTVQTRSYVIKLASDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGDG
Download Length: 747 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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