Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-PHD
Location 446438..447081 Replicon chromosome
Accession NZ_CP103289
Organism Cellulomonas sp. NS3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXY84_RS02075 Protein ID WP_258725523.1
Coordinates 446438..446821 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXY84_RS02080 Protein ID WP_258725524.1
Coordinates 446818..447081 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXY84_RS02055 441799..442914 + 1116 WP_258725519.1 serine protease -
NXY84_RS02060 442943..444232 - 1290 WP_258725520.1 hypothetical protein -
NXY84_RS02065 444311..445204 + 894 WP_258725521.1 helix-turn-helix transcriptional regulator -
NXY84_RS02070 445317..446357 + 1041 WP_258725522.1 NAD(P)-dependent alcohol dehydrogenase -
NXY84_RS02075 446438..446821 - 384 WP_258725523.1 PIN domain-containing protein Toxin
NXY84_RS02080 446818..447081 - 264 WP_258725524.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NXY84_RS02085 447155..447454 - 300 WP_258725525.1 hypothetical protein -
NXY84_RS02090 447444..449063 - 1620 WP_258725526.1 TROVE domain-containing protein -
NXY84_RS02095 449907..451073 + 1167 WP_258725527.1 hypothetical protein -
NXY84_RS02100 451124..451276 - 153 WP_258725528.1 hypothetical protein -
NXY84_RS02105 451287..451631 - 345 WP_258727094.1 DUF1796 family putative cysteine peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-109)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-43)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13245.32 Da        Isoelectric Point: 6.4691

>T254855 WP_258725523.1 NZ_CP103289:c446821-446438 [Cellulomonas sp. NS3]
VRLILDTNVLIDRLVPTGRGDEAAISMATLAELRFGVLMARTPESRAARMRVLSGAESALTALPIDDAVASSYALLATKT
VAAGRQPRARAFDLLIAATAHAHGGVLITSPVGDFAGLEGVLEVREP

Download         Length: 384 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9690.88 Da        Isoelectric Point: 4.6736

>AT254855 WP_258725524.1 NZ_CP103289:c447081-446818 [Cellulomonas sp. NS3]
MTTVGVRELRQDASGVLRHVEEGERVVVTVHGRPVADLVPHSEARPMWRPVAELAALFPGVDDPHWDEDMALVDGAARDP
FERDTPR

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References