Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 1220255..1220781 Replicon chromosome
Accession NZ_CP103288
Organism Pseudarthrobacter sp. NS4

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NXY83_RS05755 Protein ID WP_258805119.1
Coordinates 1220455..1220781 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NXY83_RS05750 Protein ID WP_258805118.1
Coordinates 1220255..1220458 (+) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXY83_RS05725 1215653..1216573 + 921 WP_258805112.1 ABC transporter permease -
NXY83_RS05730 1216570..1217418 + 849 WP_258805113.1 ABC transporter ATP-binding protein -
NXY83_RS05735 1217415..1218311 + 897 WP_258805114.1 ATP-binding cassette domain-containing protein -
NXY83_RS05740 1218311..1219288 + 978 WP_258805116.1 aldo/keto reductase -
NXY83_RS05745 1219358..1220119 + 762 WP_258805117.1 aldolase/citrate lyase family protein -
NXY83_RS05750 1220255..1220458 + 204 WP_258805118.1 antitoxin MazE family protein Antitoxin
NXY83_RS05755 1220455..1220781 + 327 WP_258805119.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NXY83_RS05760 1220867..1221214 - 348 WP_258806078.1 PH domain-containing protein -
NXY83_RS05765 1221292..1221768 - 477 WP_258805120.1 HNH endonuclease signature motif containing protein -
NXY83_RS05770 1221964..1223172 - 1209 WP_258806079.1 DUF3322 and DUF2220 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-103)

Antitoxin

Antitoxin MazE-like

(4-65)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11647.37 Da        Isoelectric Point: 4.5557

>T254854 WP_258805119.1 NZ_CP103288:1220455-1220781 [Pseudarthrobacter sp. NS4]
VNRGELWTVSGGIYAQKPRPALIIQDDLFEASESVTLLPLTSQLTDAPILRLTVEPGDLTGLERESQIMVDKLTTVRRAN
LGQRVGQVDAKTMAAVEQSLAVFLGLGS

Download         Length: 327 bp

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7994.99 Da        Isoelectric Point: 5.1532

>AT254854 WP_258805118.1 NZ_CP103288:1220255-1220458 [Pseudarthrobacter sp. NS4]
MSVRDRVARHRIAMRERGLRQIQMWVPDIRTEEFKREARRQALAVAAADRAADDQDFIEEISEDWPE

Download         Length: 204 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References