Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/Txe-RelB
Location 6250157..6250677 Replicon chromosome
Accession NZ_CP103068
Organism Bacteroides sp. BFG-257

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NXV86_RS25030 Protein ID WP_224320138.1
Coordinates 6250408..6250677 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NXV86_RS25025 Protein ID WP_224320137.1
Coordinates 6250157..6250411 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXV86_RS25005 (NXV86_25005) 6245209..6245763 - 555 WP_217714731.1 RNA polymerase sigma-70 factor -
NXV86_RS25010 (NXV86_25010) 6245921..6247666 + 1746 WP_224320136.1 pectate lyase -
NXV86_RS25015 (NXV86_25015) 6247841..6248542 + 702 WP_007664170.1 nitrogen-fixing protein NifU -
NXV86_RS25020 (NXV86_25020) 6248562..6249573 + 1012 Protein_4932 GGGtGRT protein -
NXV86_RS25025 (NXV86_25025) 6250157..6250411 + 255 WP_224320137.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NXV86_RS25030 (NXV86_25030) 6250408..6250677 + 270 WP_224320138.1 Txe/YoeB family addiction module toxin Toxin
NXV86_RS25035 (NXV86_25035) 6251249..6252073 + 825 WP_258771085.1 leucine-rich repeat domain-containing protein -
NXV86_RS25040 (NXV86_25040) 6252027..6252848 + 822 WP_258771086.1 leucine-rich repeat domain-containing protein -
NXV86_RS25045 (NXV86_25045) 6253598..6255556 + 1959 WP_224320140.1 LruC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10844.65 Da        Isoelectric Point: 10.1205

>T254849 WP_224320138.1 NZ_CP103068:6250408-6250677 [Bacteroides sp. BFG-257]
MKVIFSPLAMEQWEYWKKNNPNIAKRIKKILLDIREHPYTGIAKPEPLKYDLAGKWSRRINEEHRIIYSVNDDRIEIDIL
SMRYHYSKK

Download         Length: 270 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9406.50 Da        Isoelectric Point: 4.0721

>AT254849 WP_224320137.1 NZ_CP103068:6250157-6250411 [Bacteroides sp. BFG-257]
MRTANYTDLRANLKGYIDSVIDDYDTVIVNRGNGKGVVMISLDEYNSLKETEYIMSSPATMEAIRQGEEDIKNGKGIEVD
LDEL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References