Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 4070265..4070892 Replicon chromosome
Accession NZ_CP103057
Organism Sphingomonas sp. ZFBP2030

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NV382_RS19445 Protein ID WP_260598505.1
Coordinates 4070485..4070892 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NV382_RS19440 Protein ID WP_260598504.1
Coordinates 4070265..4070495 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV382_RS19420 4066255..4066998 - 744 WP_260598500.1 class I SAM-dependent methyltransferase -
NV382_RS19425 4067055..4067867 + 813 WP_260598501.1 bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase -
NV382_RS19430 4067977..4068240 + 264 WP_260598502.1 30S ribosomal protein S20 -
NV382_RS19435 4068708..4070093 + 1386 WP_260598503.1 chromosomal replication initiator protein DnaA -
NV382_RS19440 4070265..4070495 + 231 WP_260598504.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NV382_RS19445 4070485..4070892 + 408 WP_260598505.1 PIN domain-containing protein Toxin
NV382_RS19450 4071000..4072007 - 1008 WP_260598506.1 tryptophan--tRNA ligase -
NV382_RS19455 4072019..4073593 - 1575 WP_260598507.1 murein biosynthesis integral membrane protein MurJ -
NV382_RS19460 4073734..4074249 - 516 WP_260598508.1 protein-export chaperone SecB -
NV382_RS19465 4074480..4075124 + 645 WP_260598509.1 Tim44/TimA family putative adaptor protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-114)

Antitoxin

SpoVT-AbrB domain

(5-42)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14549.71 Da        Isoelectric Point: 4.6736

>T254827 WP_260598505.1 NZ_CP103057:4070485-4070892 [Sphingomonas sp. ZFBP2030]
MPGSFFDSNVPLSVAVGDDAKANLAEQLLSSGGIVSVQVLNEVANVALRKYGFTIPEVVTFIDSLRFVVKVVPVTVETHE
VALIVRERHRFAFHDCAIVAAALLADCETLWSEDMHDGLVVDGRLTIRNPFAGAA

Download         Length: 408 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8610.99 Da        Isoelectric Point: 10.5847

>AT254827 WP_260598504.1 NZ_CP103057:4070265-4070495 [Sphingomonas sp. ZFBP2030]
MQVAKWGNSLAVRLPKHVVLALDLKAGDDVTLRAREPGTLDVSKTMTREEALMNLRRFRGMIPADFKFDRDEANAR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References