Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1901359..1901504 Replicon chromosome
Accession NZ_CP102993
Organism Klebsiella pneumoniae strain KPA3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1901395..1901497 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1901359..1901504 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW255_RS09215 1896489..1898549 + 2061 WP_004151449.1 oligopeptidase B -
NW255_RS09220 1898553..1899212 - 660 WP_020324964.1 exodeoxyribonuclease X -
NW255_RS09225 1899291..1899521 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NW255_RS09230 1899634..1900008 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NW255_RS09235 1900012..1900881 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NW255_RS09240 1900898..1901236 + 339 WP_002911404.1 YebY family protein -
- 1901359..1901504 - 146 - - Antitoxin
- 1901395..1901497 + 103 - - Toxin
NW255_RS09245 1901873..1902016 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NW255_RS09250 1902121..1903089 - 969 WP_004151446.1 VirK/YbjX family protein -
NW255_RS09255 1903246..1903899 + 654 WP_258825667.1 protein-serine/threonine phosphatase -
NW255_RS09260 1903896..1904087 - 192 WP_002911395.1 YebW family protein -
NW255_RS09265 1904185..1904424 - 240 WP_002911393.1 YebV family protein -
NW255_RS09270 1904540..1905973 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254813 NZ_CP102993:1901395-1901497 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254813 NZ_CP102993:c1901504-1901359 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References