Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1882582..1882727 Replicon chromosome
Accession NZ_CP102987
Organism Klebsiella pneumoniae strain KPA2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1882618..1882720 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1882582..1882727 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW253_RS09065 1877712..1879772 + 2061 WP_004151449.1 oligopeptidase B -
NW253_RS09070 1879776..1880435 - 660 WP_002911407.1 exodeoxyribonuclease X -
NW253_RS09075 1880514..1880744 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NW253_RS09080 1880857..1881231 + 375 WP_039819395.1 CopC domain-containing protein YobA -
NW253_RS09085 1881235..1882104 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
NW253_RS09090 1882121..1882459 + 339 WP_002911404.1 YebY family protein -
- 1882582..1882727 - 146 - - Antitoxin
- 1882618..1882720 + 103 - - Toxin
NW253_RS09095 1883096..1883239 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
NW253_RS09100 1883344..1884312 - 969 WP_014907334.1 VirK/YbjX family protein -
NW253_RS09105 1884469..1885122 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
NW253_RS09110 1885119..1885310 - 192 WP_002911395.1 YebW family protein -
NW253_RS09115 1885408..1885647 - 240 WP_002911393.1 YebV family protein -
NW253_RS09120 1885763..1887196 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254796 NZ_CP102987:1882618-1882720 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254796 NZ_CP102987:c1882727-1882582 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References