254767

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 820540..821017 Replicon chromosome
Accession NZ_CP102975
Organism Staphylococcus aureus strain 16CS0209

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag NW953_RS03870 Protein ID WP_000052076.1
Coordinates 820540..820728 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag NW953_RS03875 Protein ID WP_001059690.1
Coordinates 820757..821017 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW953_RS03840 (NW953_03840) 816494..817051 + 558 WP_258409790.1 hypothetical protein -
NW953_RS03845 (NW953_03845) 817392..818078 + 687 WP_258409791.1 thermonuclease family protein -
NW953_RS03850 (NW953_03850) 818435..818635 + 201 WP_001059082.1 cold-shock protein -
NW953_RS03855 (NW953_03855) 819132..819350 - 219 WP_000005884.1 hypothetical protein -
NW953_RS03860 (NW953_03860) 819411..819695 - 285 WP_123097411.1 hypothetical protein -
NW953_RS03865 (NW953_03865) 819783..820352 - 570 WP_123097410.1 lipoprotein N-acylation protein LnsA -
NW953_RS03870 (NW953_03870) 820540..820728 - 189 WP_000052076.1 hypothetical protein Toxin
NW953_RS03875 (NW953_03875) 820757..821017 - 261 WP_001059690.1 hypothetical protein Antitoxin
NW953_RS03880 (NW953_03880) 821358..821561 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
NW953_RS03885 (NW953_03885) 821558..821794 - 237 WP_000368687.1 hypothetical protein -
NW953_RS03890 (NW953_03890) 822019..822600 + 582 WP_001140696.1 histidine phosphatase family protein -
NW953_RS03895 (NW953_03895) 822673..823290 - 618 WP_258409792.1 LysE/ArgO family amino acid transporter -
NW953_RS03900 (NW953_03900) 823447..823941 - 495 WP_000569881.1 GNAT family N-acetyltransferase -
NW953_RS03905 (NW953_03905) 824340..824762 - 423 WP_000974455.1 organic hydroperoxide resistance protein -
NW953_RS03910 (NW953_03910) 824910..825626 + 717 WP_258409793.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T254767 WP_000052076.1 NZ_CP102975:c820728-820540 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT254767 WP_001059690.1 NZ_CP102975:c821017-820757 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References