254747

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 823474..823951 Replicon chromosome
Accession NZ_CP102972
Organism Staphylococcus aureus strain 05-RR-90

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag NW963_RS03925 Protein ID WP_000052076.1
Coordinates 823474..823662 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag NW963_RS03930 Protein ID WP_001059690.1
Coordinates 823691..823951 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW963_RS03895 (NW963_03895) 819428..819985 + 558 WP_258412467.1 hypothetical protein -
NW963_RS03900 (NW963_03900) 820326..821012 + 687 WP_258412468.1 thermonuclease family protein -
NW963_RS03905 (NW963_03905) 821369..821569 + 201 WP_001059082.1 cold-shock protein -
NW963_RS03910 (NW963_03910) 822065..822283 - 219 WP_000005876.1 hypothetical protein -
NW963_RS03915 (NW963_03915) 822345..822629 - 285 WP_001004394.1 hypothetical protein -
NW963_RS03920 (NW963_03920) 822717..823286 - 570 WP_001106652.1 lipoprotein N-acylation protein LnsA -
NW963_RS03925 (NW963_03925) 823474..823662 - 189 WP_000052076.1 hypothetical protein Toxin
NW963_RS03930 (NW963_03930) 823691..823951 - 261 WP_001059690.1 hypothetical protein Antitoxin
NW963_RS03935 (NW963_03935) 824292..824495 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
NW963_RS03940 (NW963_03940) 824492..824728 - 237 WP_000368687.1 hypothetical protein -
NW963_RS03945 (NW963_03945) 824953..825534 + 582 WP_001140697.1 histidine phosphatase family protein -
NW963_RS03950 (NW963_03950) 825607..826224 - 618 WP_086153000.1 LysE/ArgO family amino acid transporter -
NW963_RS03955 (NW963_03955) 826379..826873 - 495 WP_086153001.1 GNAT family N-acetyltransferase -
NW963_RS03960 (NW963_03960) 827271..827693 - 423 WP_000974455.1 organic hydroperoxide resistance protein -
NW963_RS03965 (NW963_03965) 827841..828557 + 717 WP_000150012.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T254747 WP_000052076.1 NZ_CP102972:c823662-823474 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT254747 WP_001059690.1 NZ_CP102972:c823951-823691 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References