254700

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 814428..814905 Replicon chromosome
Accession NZ_CP102966
Organism Staphylococcus aureus strain 29-P-01

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag NW955_RS03825 Protein ID WP_000052076.1
Coordinates 814428..814616 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag NW955_RS03830 Protein ID WP_001059690.1
Coordinates 814645..814905 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW955_RS03795 (NW955_03795) 810430..810939 + 510 WP_258412868.1 hypothetical protein -
NW955_RS03800 (NW955_03800) 811280..811966 + 687 WP_258412869.1 thermonuclease family protein -
NW955_RS03805 (NW955_03805) 812323..812523 + 201 WP_001059082.1 cold-shock protein -
NW955_RS03810 (NW955_03810) 813019..813237 - 219 WP_000005884.1 hypothetical protein -
NW955_RS03815 (NW955_03815) 813299..813583 - 285 WP_001004395.1 hypothetical protein -
NW955_RS03820 (NW955_03820) 813671..814240 - 570 WP_258412870.1 lipoprotein N-acylation protein LnsA -
NW955_RS03825 (NW955_03825) 814428..814616 - 189 WP_000052076.1 hypothetical protein Toxin
NW955_RS03830 (NW955_03830) 814645..814905 - 261 WP_001059690.1 hypothetical protein Antitoxin
NW955_RS03835 (NW955_03835) 815245..815448 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
NW955_RS03840 (NW955_03840) 815445..815681 - 237 WP_000368687.1 hypothetical protein -
NW955_RS03845 (NW955_03845) 815905..816486 + 582 WP_001140697.1 histidine phosphatase family protein -
NW955_RS03850 (NW955_03850) 816559..817176 - 618 WP_000255553.1 LysE/ArgO family amino acid transporter -
NW955_RS03855 (NW955_03855) 817331..817825 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
NW955_RS03860 (NW955_03860) 818224..818646 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
NW955_RS03865 (NW955_03865) 818794..819510 + 717 WP_258412871.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T254700 WP_000052076.1 NZ_CP102966:c814616-814428 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT254700 WP_001059690.1 NZ_CP102966:c814905-814645 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References