Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 5611592..5613297 Replicon chromosome
Accession NZ_CP102951
Organism Pseudomonas sp. LS1212

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag NVV94_RS26310 Protein ID WP_258445179.1
Coordinates 5611592..5612473 (+) Length 294 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag NVV94_RS26315 Protein ID WP_258445180.1
Coordinates 5612470..5613297 (+) Length 276 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVV94_RS26285 (NVV94_26285) 5607588..5608424 + 837 WP_258447831.1 ABC transporter ATP-binding protein -
NVV94_RS26290 (NVV94_26290) 5608464..5609465 + 1002 WP_258445176.1 ABC transporter substrate-binding protein -
NVV94_RS26295 (NVV94_26295) 5609494..5610270 + 777 WP_258445177.1 ABC transporter permease -
NVV94_RS26300 (NVV94_26300) 5610270..5611034 + 765 WP_258447832.1 SDR family oxidoreductase -
NVV94_RS26305 (NVV94_26305) 5611048..5611587 + 540 WP_258445178.1 cupin domain-containing protein -
NVV94_RS26310 (NVV94_26310) 5611592..5612473 + 882 WP_258445179.1 alpha/beta hydrolase Toxin
NVV94_RS26315 (NVV94_26315) 5612470..5613297 + 828 WP_258445180.1 IclR family transcriptional regulator Antitoxin
NVV94_RS26320 (NVV94_26320) 5613299..5614096 + 798 WP_258445181.1 SDR family oxidoreductase -
NVV94_RS26325 (NVV94_26325) 5614089..5615771 + 1683 WP_258445182.1 thiamine pyrophosphate-binding protein -
NVV94_RS26330 (NVV94_26330) 5615782..5616585 + 804 WP_258445183.1 aspartate dehydrogenase -
NVV94_RS26335 (NVV94_26335) 5616595..5618091 + 1497 WP_258445184.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-270)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 294 a.a.        Molecular weight: 30857.33 Da        Isoelectric Point: 6.6790

>T254585 WP_258445179.1 NZ_CP102951:5611592-5612473 [Pseudomonas sp. LS1212]
MQPAIFNHDPAPTAKLEALLDSQFAQRELAVDDGRLAIREVGTGPAIVLLHGIGSGAASWLQVALALSQDARVIAWDAPG
YGDSTPLAHPAPSAMDYAGRLLHMLDALGIETCVLVGHSLGALTATALASSQPHRVSRLVLISPARGYGDPARETQRQQV
RAKRLQTLECLGIAQMAHERCAHMLSSRASSSALAWVQWNMSRLNPAGYRQAIELLCGDDLLRHAPLSVPCEVHCGEADA
ITAPEACHGLAKSLAASFSLIPDAGHASPIEQPIVVAGRLAHALKESLTGSAL

Download         Length: 882 bp

Antitoxin


Download         Length: 276 a.a.        Molecular weight: 30726.24 Da        Isoelectric Point: 6.3488

>AT254585 WP_258445180.1 NZ_CP102951:5612470-5613297 [Pseudomonas sp. LS1212]
MNDSDLLKDTQDKYIVPGLERGLLLLCEFSRQNRTLTAPELARRLELPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLTLA
ELRDLYPEDHLEQYSPCTPKTVLELFDLVQGDRQRGFVSGEGFFESAISTVAAPVRDHTSRIVAALGVTIPTVQIGHVNF
EELLSQVRRSADELSRLLNYTPNVGHNRVTALMRD

Download         Length: 828 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References