Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 1710214..1711253 | Replicon | chromosome |
| Accession | NZ_CP102951 | ||
| Organism | Pseudomonas sp. LS1212 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | NVV94_RS08005 | Protein ID | WP_258446666.1 |
| Coordinates | 1710214..1710789 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | NVV94_RS08010 | Protein ID | WP_258446667.1 |
| Coordinates | 1710786..1711253 (-) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NVV94_RS07985 (NVV94_07985) | 1706039..1706863 | - | 825 | WP_258446663.1 | ion transporter | - |
| NVV94_RS07990 (NVV94_07990) | 1707429..1707770 | + | 342 | WP_258446664.1 | hypothetical protein | - |
| NVV94_RS07995 (NVV94_07995) | 1707774..1708936 | - | 1163 | Protein_1554 | IS3 family transposase | - |
| NVV94_RS08000 (NVV94_08000) | 1709549..1709884 | - | 336 | WP_258446665.1 | DUF3077 domain-containing protein | - |
| NVV94_RS08005 (NVV94_08005) | 1710214..1710789 | - | 576 | WP_258446666.1 | PIN domain-containing protein | Toxin |
| NVV94_RS08010 (NVV94_08010) | 1710786..1711253 | - | 468 | WP_258446667.1 | helix-turn-helix domain-containing protein | Antitoxin |
| NVV94_RS08015 (NVV94_08015) | 1711964..1712881 | - | 918 | WP_258446668.1 | urea transporter | - |
| NVV94_RS08020 (NVV94_08020) | 1713093..1714508 | - | 1416 | WP_258446669.1 | pyruvate kinase | - |
| NVV94_RS08025 (NVV94_08025) | 1714498..1715778 | - | 1281 | WP_258446670.1 | glycerate kinase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1699634..1717792 | 18158 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21973.17 Da Isoelectric Point: 4.6593
>T254583 WP_258446666.1 NZ_CP102951:c1710789-1710214 [Pseudomonas sp. LS1212]
MRHSPFTAVFDACVLYPAPLRSLLMWLSLTGLYRARWTEQIHEEWKRNLLINRDDLTREQLDRTSELMDRSIPDALVTGY
ESLCADLSLPDPDDRHVLAAAIRCKAEVIVTFNLKDFPVERLDGYDIEAIHPDDFIADLWDLDQAAVLSAVQDQRRSLKS
PPMTGQQYLEMILRQGLTQTVRNLTPYIGML
MRHSPFTAVFDACVLYPAPLRSLLMWLSLTGLYRARWTEQIHEEWKRNLLINRDDLTREQLDRTSELMDRSIPDALVTGY
ESLCADLSLPDPDDRHVLAAAIRCKAEVIVTFNLKDFPVERLDGYDIEAIHPDDFIADLWDLDQAAVLSAVQDQRRSLKS
PPMTGQQYLEMILRQGLTQTVRNLTPYIGML
Download Length: 576 bp
Antitoxin
Download Length: 156 a.a. Molecular weight: 17629.17 Da Isoelectric Point: 5.6392
>AT254583 WP_258446667.1 NZ_CP102951:c1711253-1710786 [Pseudomonas sp. LS1212]
MIATELSRTILPVEREVAAATEGQRTLATFLSTQRETQLIEIFDKDDKPHKIELPTSALRLLVDILGELAIGNAVKVVPI
HAELTTQEAADLLNVSRPHLIKLLEEGALPFTRTGRHRRVRFSDLMAYKQHRDEDSRQTMESLTQLDQELRMGYE
MIATELSRTILPVEREVAAATEGQRTLATFLSTQRETQLIEIFDKDDKPHKIELPTSALRLLVDILGELAIGNAVKVVPI
HAELTTQEAADLLNVSRPHLIKLLEEGALPFTRTGRHRRVRFSDLMAYKQHRDEDSRQTMESLTQLDQELRMGYE
Download Length: 468 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|