Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1136597..1137079 Replicon chromosome
Accession NZ_CP102951
Organism Pseudomonas sp. LS1212

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NVV94_RS05170 Protein ID WP_258446163.1
Coordinates 1136951..1137079 (-) Length 43 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NVV94_RS05165 Protein ID WP_258446162.1
Coordinates 1136597..1136878 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVV94_RS05140 (NVV94_05140) 1131802..1132626 - 825 WP_258446157.1 ABC transporter permease -
NVV94_RS05145 (NVV94_05145) 1132623..1133432 - 810 WP_258446158.1 phosphonate ABC transporter ATP-binding protein -
NVV94_RS05150 (NVV94_05150) 1133429..1134280 - 852 WP_258446159.1 putative selenate ABC transporter substrate-binding protein -
NVV94_RS05155 (NVV94_05155) 1134367..1135470 - 1104 WP_258446160.1 tRNA 2-selenouridine(34) synthase MnmH -
NVV94_RS05160 (NVV94_05160) 1135470..1136504 - 1035 WP_258446161.1 selenide, water dikinase SelD -
NVV94_RS05165 (NVV94_05165) 1136597..1136878 - 282 WP_258446162.1 putative addiction module antidote protein Antitoxin
NVV94_RS05170 (NVV94_05170) 1136951..1137079 - 129 WP_258446163.1 hypothetical protein Toxin
NVV94_RS05175 (NVV94_05175) 1137199..1137432 + 234 Protein_1008 LysR family transcriptional regulator -
NVV94_RS05180 (NVV94_05180) 1137422..1137532 + 111 Protein_1009 hydroxymethylglutaryl-CoA lyase -
NVV94_RS05185 (NVV94_05185) 1137521..1137789 + 269 Protein_1010 MFS transporter -
NVV94_RS05190 (NVV94_05190) 1137906..1138769 - 864 WP_258446164.1 universal stress protein -
NVV94_RS05195 (NVV94_05195) 1139229..1139450 - 222 WP_258446165.1 formate dehydrogenase subunit delta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(37-89)


Sequences

Toxin        


Download         Length: 43 a.a.        Molecular weight: 4823.57 Da        Isoelectric Point: 9.5008

>T254582 WP_258446163.1 NZ_CP102951:c1137079-1136951 [Pseudomonas sp. LS1212]
MNTLITTQEFDRWLDALKDFKARARIVTRIISAEQGNAAVCR

Download         Length: 129 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10246.73 Da        Isoelectric Point: 6.4666

>AT254582 WP_258446162.1 NZ_CP102951:c1136878-1136597 [Pseudomonas sp. LS1212]
MSQLKTFEPSKYLTDEDTIAEFLTASLEDENPDVFLRALQEVAKARGMSQLAKDAGINRESLYKALAPGAKPRYDTVLKL
LNALGVKLTAHHA

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References