Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 640263..640909 Replicon chromosome
Accession NZ_CP102951
Organism Pseudomonas sp. LS1212

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NVV94_RS02890 Protein ID WP_258445757.1
Coordinates 640493..640909 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NVV94_RS02885 Protein ID WP_258445756.1
Coordinates 640263..640493 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVV94_RS02865 (NVV94_02865) 635470..636006 + 537 WP_258445752.1 NUDIX hydrolase -
NVV94_RS02870 (NVV94_02870) 636191..636562 + 372 WP_258445753.1 translation initiation factor Sui1 -
NVV94_RS02875 (NVV94_02875) 636761..638674 + 1914 WP_258445754.1 arginine decarboxylase -
NVV94_RS02880 (NVV94_02880) 638815..640164 - 1350 WP_258445755.1 MATE family efflux transporter -
NVV94_RS02885 (NVV94_02885) 640263..640493 + 231 WP_258445756.1 antitoxin Antitoxin
NVV94_RS02890 (NVV94_02890) 640493..640909 + 417 WP_258445757.1 tRNA(fMet)-specific endonuclease VapC Toxin
NVV94_RS02895 (NVV94_02895) 640997..645907 + 4911 WP_258445758.1 alpha-2-macroglobulin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-34)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15219.57 Da        Isoelectric Point: 7.3831

>T254581 WP_258445757.1 NZ_CP102951:640493-640909 [Pseudomonas sp. LS1212]
MLKYMLDTNICIFTLKNKPQEVREAFTRHHGQLCISTVTLMELIYGAEKSAAPEKNLAVIEGFAARLEVLSYDNQAAAHS
GQLRAELAKSGKPIGPYDQMIAGHARSLGLILVTNNLGEFERVKGLRLEDWVNAHAIG

Download         Length: 417 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8497.43 Da        Isoelectric Point: 4.2958

>AT254581 WP_258445756.1 NZ_CP102951:640263-640493 [Pseudomonas sp. LS1212]
MEQGAVFKSNRSQAVRLPKAVALPDDVTRVDVVAIGRARLITPAGESWDSWFEGESVSVDFMSEREQPADQERETF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References