254580

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 603444..603991 Replicon chromosome
Accession NZ_CP102951
Organism Pseudomonas sp. LS1212

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NVV94_RS02720 Protein ID WP_258445723.1
Coordinates 603444..603719 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NVV94_RS02725 Protein ID WP_258445724.1
Coordinates 603719..603991 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVV94_RS02705 (NVV94_02705) 599143..600222 - 1080 WP_258445720.1 urea ABC transporter permease subunit UrtC -
NVV94_RS02710 (NVV94_02710) 600222..601718 - 1497 WP_258445721.1 urea ABC transporter permease subunit UrtB -
NVV94_RS02715 (NVV94_02715) 601893..603158 - 1266 WP_258445722.1 urea ABC transporter substrate-binding protein -
NVV94_RS02720 (NVV94_02720) 603444..603719 - 276 WP_258445723.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NVV94_RS02725 (NVV94_02725) 603719..603991 - 273 WP_258445724.1 ribbon-helix-helix domain-containing protein Antitoxin
NVV94_RS02730 (NVV94_02730) 604255..604404 + 150 WP_258445725.1 hypothetical protein -
NVV94_RS02735 (NVV94_02735) 604544..605914 - 1371 WP_258445726.1 PepSY domain-containing protein -
NVV94_RS02740 (NVV94_02740) 605981..606445 - 465 WP_258445727.1 DUF2946 domain-containing protein -
NVV94_RS02745 (NVV94_02745) 606458..606937 - 480 WP_258445728.1 copper chaperone PCu(A)C -
NVV94_RS02750 (NVV94_02750) 606983..607366 - 384 WP_258445729.1 DUF2946 domain-containing protein -
NVV94_RS02755 (NVV94_02755) 607571..608299 - 729 WP_258445730.1 cobalt-precorrin-6A reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10773.34 Da        Isoelectric Point: 7.2018

>T254580 WP_258445723.1 NZ_CP102951:c603719-603444 [Pseudomonas sp. LS1212]
MELKWTSKALSDLTRLYEFLATANQPAAARTVQQLIAAPTTLLNNPRIGEWLEEFEPRDVRRILVGHYEMRYEIQGSTIY
LLRLWHTREDR

Download         Length: 276 bp

>T254580 NZ_CP102951:c603719-603444 [Pseudomonas sp. LS1212]
ATGGAGTTGAAGTGGACAAGCAAGGCACTTTCCGACCTGACCCGGCTCTATGAATTCCTGGCCACGGCCAACCAACCCGC
CGCGGCACGAACGGTTCAGCAGCTCATAGCTGCACCGACCACGCTGTTGAACAACCCGCGAATTGGCGAGTGGCTGGAAG
AGTTCGAACCGCGTGATGTGCGGCGGATCTTGGTCGGTCACTATGAAATGCGCTACGAGATTCAAGGCTCGACGATTTAT
CTGTTGCGTCTGTGGCATACACGCGAGGATCGCTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10114.45 Da        Isoelectric Point: 6.4662

>AT254580 WP_258445724.1 NZ_CP102951:c603991-603719 [Pseudomonas sp. LS1212]
MTRTANTRVVTAHIPVQLAEKIDQMATRIERSKGWIVKQALAAWIDQEEERSRLTREALADVDVGRVIDHQAVQAWADSL
STDNPLPAPR

Download         Length: 273 bp

>AT254580 NZ_CP102951:c603991-603719 [Pseudomonas sp. LS1212]
ATGACCCGCACAGCTAACACCCGAGTCGTTACCGCTCACATCCCGGTGCAACTGGCCGAAAAGATCGATCAGATGGCTAC
ACGTATAGAGCGTTCAAAGGGCTGGATCGTCAAACAAGCACTCGCCGCGTGGATCGACCAGGAAGAAGAGCGCAGTCGCC
TGACCCGTGAAGCACTCGCCGATGTCGACGTCGGTCGGGTTATCGACCATCAGGCTGTTCAAGCCTGGGCCGACAGCCTC
AGCACCGACAACCCGTTGCCGGCACCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References