Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1957023..1957168 Replicon chromosome
Accession NZ_CP102940
Organism Klebsiella pneumoniae strain SCAID PND1-2022 (426)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1957059..1957161 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1957023..1957168 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW340_RS09475 1952153..1954213 + 2061 WP_004151449.1 oligopeptidase B -
NW340_RS09480 1954217..1954876 - 660 WP_002911407.1 exodeoxyribonuclease X -
NW340_RS09485 1954955..1955185 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NW340_RS09490 1955298..1955672 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NW340_RS09495 1955676..1956545 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
NW340_RS09500 1956562..1956900 + 339 WP_002911404.1 YebY family protein -
- 1957023..1957168 - 146 - - Antitoxin
- 1957059..1957161 + 103 - - Toxin
NW340_RS09505 1957536..1957679 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NW340_RS09510 1957784..1958752 - 969 WP_004151446.1 VirK/YbjX family protein -
NW340_RS09515 1958909..1959562 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
NW340_RS09520 1959559..1959750 - 192 WP_002911395.1 YebW family protein -
NW340_RS09525 1959848..1960087 - 240 WP_002911393.1 YebV family protein -
NW340_RS09530 1960203..1961636 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254509 NZ_CP102940:1957059-1957161 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254509 NZ_CP102940:c1957168-1957023 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References