Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3333757..3334410 Replicon chromosome
Accession NZ_CP102934
Organism Acinetobacter sp. AOR07_HL

Toxin (Protein)


Gene name cptA Uniprot ID A0A9E9PBS3
Locus tag MKL45_RS15740 Protein ID WP_002096593.1
Coordinates 3333757..3334146 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MKL45_RS15745 Protein ID WP_001288210.1
Coordinates 3334153..3334410 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKL45_RS15725 (MKL45_15730) 3328875..3331070 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
MKL45_RS15730 (MKL45_15735) 3331258..3331824 - 567 WP_000651536.1 rhombosortase -
MKL45_RS15735 (MKL45_15740) 3331902..3332987 - 1086 WP_000049106.1 hypothetical protein -
MKL45_RS15740 (MKL45_15745) 3333757..3334146 - 390 WP_002096593.1 hypothetical protein Toxin
MKL45_RS15745 (MKL45_15750) 3334153..3334410 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MKL45_RS15750 (MKL45_15755) 3334598..3335770 + 1173 WP_001190548.1 acyl-CoA dehydrogenase family protein -
MKL45_RS15755 (MKL45_15760) 3335819..3337309 - 1491 WP_004745487.1 NAD(P)/FAD-dependent oxidoreductase -
MKL45_RS15760 (MKL45_15765) 3337491..3337868 - 378 WP_001216380.1 50S ribosomal protein L17 -
MKL45_RS15765 (MKL45_15770) 3337887..3338894 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15677.99 Da        Isoelectric Point: 10.3890

>T254502 WP_002096593.1 NZ_CP102934:c3334146-3333757 [Acinetobacter sp. AOR07_HL]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT254502 WP_001288210.1 NZ_CP102934:c3334410-3334153 [Acinetobacter sp. AOR07_HL]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References