Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3836508..3837165 Replicon chromosome
Accession NZ_CP102932
Organism Enterobacter sp. Crenshaw

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NWV12_RS18170 Protein ID WP_101744679.1
Coordinates 3836508..3836918 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V3PWU7
Locus tag NWV12_RS18175 Protein ID WP_010435322.1
Coordinates 3836899..3837165 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWV12_RS18150 (NWV12_18150) 3832501..3834234 - 1734 WP_039262981.1 single-stranded-DNA-specific exonuclease RecJ -
NWV12_RS18155 (NWV12_18155) 3834240..3834953 - 714 WP_047060452.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NWV12_RS18160 (NWV12_18160) 3834982..3835878 - 897 WP_023309098.1 site-specific tyrosine recombinase XerD -
NWV12_RS18165 (NWV12_18165) 3835980..3836501 + 522 WP_039262979.1 flavodoxin FldB -
NWV12_RS18170 (NWV12_18170) 3836508..3836918 - 411 WP_101744679.1 protein YgfX Toxin
NWV12_RS18175 (NWV12_18175) 3836899..3837165 - 267 WP_010435322.1 FAD assembly factor SdhE Antitoxin
NWV12_RS18180 (NWV12_18180) 3837460..3838440 + 981 WP_029739202.1 tRNA-modifying protein YgfZ -
NWV12_RS18185 (NWV12_18185) 3838515..3839174 - 660 WP_033146591.1 hemolysin III family protein -
NWV12_RS18190 (NWV12_18190) 3839340..3839651 - 312 WP_048980550.1 N(4)-acetylcytidine aminohydrolase -
NWV12_RS18195 (NWV12_18195) 3839703..3840434 + 732 WP_032660101.1 MurR/RpiR family transcriptional regulator -
NWV12_RS18200 (NWV12_18200) 3840551..3841984 + 1434 WP_048980547.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16071.00 Da        Isoelectric Point: 10.9468

>T254497 WP_101744679.1 NZ_CP102932:c3836918-3836508 [Enterobacter sp. Crenshaw]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLSQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT254497 WP_010435322.1 NZ_CP102932:c3837165-3836899 [Enterobacter sp. Crenshaw]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB V3PWU7

References