Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 1639176..1639973 Replicon chromosome
Accession NZ_CP102932
Organism Enterobacter sp. Crenshaw

Toxin (Protein)


Gene name ataT Uniprot ID A0A808IDQ0
Locus tag NWV12_RS07685 Protein ID WP_048979073.1
Coordinates 1639452..1639973 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag NWV12_RS07680 Protein ID WP_023311079.1
Coordinates 1639176..1639445 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWV12_RS07650 (NWV12_07650) 1634803..1635246 - 444 WP_032658095.1 helix-turn-helix domain-containing protein -
NWV12_RS07655 (NWV12_07655) 1635399..1636640 + 1242 WP_048979071.1 bifunctional glucose-1-phosphatase/inositol phosphatase -
NWV12_RS07660 (NWV12_07660) 1636674..1636901 - 228 WP_008499832.1 YccJ family protein -
NWV12_RS07665 (NWV12_07665) 1636922..1637518 - 597 WP_023311076.1 NAD(P)H:quinone oxidoreductase -
NWV12_RS07670 (NWV12_07670) 1637909..1638079 + 171 WP_023311077.1 general stress protein -
NWV12_RS07675 (NWV12_07675) 1638197..1639114 + 918 WP_048979072.1 DMT family transporter -
NWV12_RS07680 (NWV12_07680) 1639176..1639445 + 270 WP_023311079.1 DUF1778 domain-containing protein Antitoxin
NWV12_RS07685 (NWV12_07685) 1639452..1639973 + 522 WP_048979073.1 GNAT family N-acetyltransferase Toxin
NWV12_RS07690 (NWV12_07690) 1640047..1641369 - 1323 WP_048979074.1 pyrimidine utilization transport protein G -
NWV12_RS07695 (NWV12_07695) 1641391..1641885 - 495 WP_048979075.1 pyrimidine utilization flavin reductase protein F -
NWV12_RS07700 (NWV12_07700) 1641895..1642485 - 591 WP_033145164.1 malonic semialdehyde reductase -
NWV12_RS07705 (NWV12_07705) 1642495..1643295 - 801 WP_048979076.1 pyrimidine utilization protein D -
NWV12_RS07710 (NWV12_07710) 1643303..1643689 - 387 WP_010429508.1 pyrimidine utilization protein C -
NWV12_RS07715 (NWV12_07715) 1643701..1644390 - 690 WP_033145167.1 pyrimidine utilization protein B -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(2-88)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19817.63 Da        Isoelectric Point: 6.9695

>T254490 WP_048979073.1 NZ_CP102932:1639452-1639973 [Enterobacter sp. Crenshaw]
VENLTIEMLSEGTDYDFEYFDCGEPSLNAFLAEHLVRQHNGRILRAYLLKERDRPRVLGYYTLSGSCFERAMLPSKTQQR
RIPYINVPSVTLGRLAVDKTLQGNEWGTTLVAHAMRVVYLASQAVGVHGIFVDALDERAKRFYLKQGFIPLTAENSHSLF
FPTKSIERLFEQE

Download         Length: 522 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10249.72 Da        Isoelectric Point: 5.8836

>AT254490 WP_023311079.1 NZ_CP102932:1639176-1639445 [Enterobacter sp. Crenshaw]
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWTAVMDAIDNPPEPNERLKR
AAKRLRNME

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808IDQ0

Antitoxin

Source ID Structure

References