Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 6844917..6846137 | Replicon | chromosome |
| Accession | NZ_CP102929 | ||
| Organism | Pseudomonas sp. CBS | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | NVB75_RS31320 | Protein ID | WP_258344820.1 |
| Coordinates | 6844917..6845492 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | NVB75_RS31325 | Protein ID | WP_258344821.1 |
| Coordinates | 6845580..6846137 (-) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NVB75_RS31300 (NVB75_31300) | 6840553..6841593 | + | 1041 | WP_177027103.1 | PilN domain-containing protein | - |
| NVB75_RS31305 (NVB75_31305) | 6841568..6842179 | + | 612 | WP_258344817.1 | type II secretion system protein GspM | - |
| NVB75_RS31310 (NVB75_31310) | 6842176..6842700 | + | 525 | WP_258344818.1 | DUF2531 family protein | - |
| NVB75_RS31315 (NVB75_31315) | 6842697..6844910 | + | 2214 | WP_258344819.1 | type II secretion system secretin GspD | - |
| NVB75_RS31320 (NVB75_31320) | 6844917..6845492 | - | 576 | WP_258344820.1 | HD domain-containing protein | Toxin |
| NVB75_RS31325 (NVB75_31325) | 6845580..6846137 | - | 558 | WP_258344821.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| NVB75_RS31330 (NVB75_31330) | 6846235..6846897 | - | 663 | WP_258344822.1 | RraA family protein | - |
| NVB75_RS31335 (NVB75_31335) | 6846923..6848260 | - | 1338 | WP_256576936.1 | MFS transporter | - |
| NVB75_RS31340 (NVB75_31340) | 6848358..6849587 | - | 1230 | WP_258344823.1 | pyridoxal phosphate-dependent aminotransferase | - |
| NVB75_RS31345 (NVB75_31345) | 6849584..6850240 | - | 657 | WP_258344824.1 | RraA family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21642.58 Da Isoelectric Point: 4.9800
>T254485 WP_258344820.1 NZ_CP102929:c6845492-6844917 [Pseudomonas sp. CBS]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR
Download Length: 576 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 20596.80 Da Isoelectric Point: 7.8767
>AT254485 WP_258344821.1 NZ_CP102929:c6846137-6845580 [Pseudomonas sp. CBS]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|