Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 6844917..6846137 Replicon chromosome
Accession NZ_CP102929
Organism Pseudomonas sp. CBS

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NVB75_RS31320 Protein ID WP_258344820.1
Coordinates 6844917..6845492 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NVB75_RS31325 Protein ID WP_258344821.1
Coordinates 6845580..6846137 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVB75_RS31300 (NVB75_31300) 6840553..6841593 + 1041 WP_177027103.1 PilN domain-containing protein -
NVB75_RS31305 (NVB75_31305) 6841568..6842179 + 612 WP_258344817.1 type II secretion system protein GspM -
NVB75_RS31310 (NVB75_31310) 6842176..6842700 + 525 WP_258344818.1 DUF2531 family protein -
NVB75_RS31315 (NVB75_31315) 6842697..6844910 + 2214 WP_258344819.1 type II secretion system secretin GspD -
NVB75_RS31320 (NVB75_31320) 6844917..6845492 - 576 WP_258344820.1 HD domain-containing protein Toxin
NVB75_RS31325 (NVB75_31325) 6845580..6846137 - 558 WP_258344821.1 helix-turn-helix transcriptional regulator Antitoxin
NVB75_RS31330 (NVB75_31330) 6846235..6846897 - 663 WP_258344822.1 RraA family protein -
NVB75_RS31335 (NVB75_31335) 6846923..6848260 - 1338 WP_256576936.1 MFS transporter -
NVB75_RS31340 (NVB75_31340) 6848358..6849587 - 1230 WP_258344823.1 pyridoxal phosphate-dependent aminotransferase -
NVB75_RS31345 (NVB75_31345) 6849584..6850240 - 657 WP_258344824.1 RraA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21642.58 Da        Isoelectric Point: 4.9800

>T254485 WP_258344820.1 NZ_CP102929:c6845492-6844917 [Pseudomonas sp. CBS]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR

Download         Length: 576 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20596.80 Da        Isoelectric Point: 7.8767

>AT254485 WP_258344821.1 NZ_CP102929:c6846137-6845580 [Pseudomonas sp. CBS]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References