254484

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3973769..3974285 Replicon chromosome
Accession NZ_CP102929
Organism Pseudomonas sp. CBS

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NVB75_RS18250 Protein ID WP_258342669.1
Coordinates 3973769..3974056 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NVB75_RS18255 Protein ID WP_258348672.1
Coordinates 3974046..3974285 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVB75_RS18230 (NVB75_18230) 3969353..3970300 - 948 WP_177020250.1 FecR family protein -
NVB75_RS18235 (NVB75_18235) 3970297..3970830 - 534 WP_177020251.1 RNA polymerase sigma factor -
NVB75_RS18240 (NVB75_18240) 3971042..3972100 - 1059 WP_256344485.1 haloacid dehalogenase-like hydrolase -
NVB75_RS18245 (NVB75_18245) 3972342..3973733 + 1392 WP_258342668.1 L-cystine transporter -
NVB75_RS18250 (NVB75_18250) 3973769..3974056 - 288 WP_258342669.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NVB75_RS18255 (NVB75_18255) 3974046..3974285 - 240 WP_258348672.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NVB75_RS18260 (NVB75_18260) 3974369..3974881 - 513 WP_008438965.1 dihydrofolate reductase -
NVB75_RS18265 (NVB75_18265) 3974972..3976351 + 1380 WP_258342670.1 DUF2868 domain-containing protein -
NVB75_RS18270 (NVB75_18270) 3976344..3977717 + 1374 WP_258342671.1 DUF3482 domain-containing protein -
NVB75_RS18275 (NVB75_18275) 3977714..3978268 - 555 WP_258342672.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11365.24 Da        Isoelectric Point: 10.0977

>T254484 WP_258342669.1 NZ_CP102929:c3974056-3973769 [Pseudomonas sp. CBS]
MTYNLEFDARALKEWRKLGDTVRQQLKKKLVEILTHPRIEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
RERDEVYRKATERLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8963.34 Da        Isoelectric Point: 4.7962

>AT254484 WP_258348672.1 NZ_CP102929:c3974285-3974046 [Pseudomonas sp. CBS]
MASINIRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References