Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 2124513..2125117 Replicon chromosome
Accession NZ_CP102929
Organism Pseudomonas sp. CBS

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NVB75_RS09415 Protein ID WP_258346945.1
Coordinates 2124513..2124764 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NVB75_RS09420 Protein ID WP_258346946.1
Coordinates 2124761..2125117 (+) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVB75_RS09410 (NVB75_09410) 2123340..2124323 - 984 WP_258346944.1 TauD/TfdA family dioxygenase -
NVB75_RS09415 (NVB75_09415) 2124513..2124764 + 252 WP_258346945.1 type II toxin-antitoxin system HicA family toxin Toxin
NVB75_RS09420 (NVB75_09420) 2124761..2125117 + 357 WP_258346946.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NVB75_RS09425 (NVB75_09425) 2125118..2126290 - 1173 WP_258346947.1 MFS transporter -
NVB75_RS09430 (NVB75_09430) 2126426..2127010 + 585 WP_258346948.1 TetR/AcrR family transcriptional regulator -
NVB75_RS09435 (NVB75_09435) 2127925..2129433 - 1509 WP_258346949.1 MDR family MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(20-76)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9509.99 Da        Isoelectric Point: 10.3760

>T254482 WP_258346945.1 NZ_CP102929:2124513-2124764 [Pseudomonas sp. CBS]
VSKNEKLLAKLLNEQSAFTWAERVTLLRRLGYTQIEGAGSRVRFDIGDPSAMITLHKPHPGNELKHYIRRQIIEQLKSGE
LIQ

Download         Length: 252 bp

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 12821.70 Da        Isoelectric Point: 6.8428

>AT254482 WP_258346946.1 NZ_CP102929:2124761-2125117 [Pseudomonas sp. CBS]
VNNQLKHKGYIGSIEASLEDNCLFGKLLFIKALVSYEGKTVAELDTAFCTAVDDYIETCMALGQTPEKPCKGSFNVRVGH
DLHLAAALAATRQKVTLNDLTRQALNEFLQHRGALVAG

Download         Length: 357 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References