Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 785610..786267 Replicon chromosome
Accession NZ_CP102893
Organism Klebsiella quasipneumoniae strain KA1

Toxin (Protein)


Gene name cptA Uniprot ID A0A2N4VX63
Locus tag NWT75_RS03875 Protein ID WP_023290968.1
Coordinates 785857..786267 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W8UQ37
Locus tag NWT75_RS03870 Protein ID WP_002916312.1
Coordinates 785610..785876 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWT75_RS03845 (780778) 780778..782211 - 1434 WP_065883832.1 6-phospho-beta-glucosidase -
NWT75_RS03850 (782330) 782330..783058 - 729 WP_032454033.1 MurR/RpiR family transcriptional regulator -
NWT75_RS03855 (783109) 783109..783420 + 312 WP_065883829.1 N(4)-acetylcytidine aminohydrolase -
NWT75_RS03860 (783584) 783584..784246 + 663 WP_065883827.1 hemolysin III family protein -
NWT75_RS03865 (784381) 784381..785364 - 984 WP_065883825.1 tRNA-modifying protein YgfZ -
NWT75_RS03870 (785610) 785610..785876 + 267 WP_002916312.1 FAD assembly factor SdhE Antitoxin
NWT75_RS03875 (785857) 785857..786267 + 411 WP_023290968.1 protein YgfX Toxin
NWT75_RS03880 (786274) 786274..786795 - 522 WP_004205324.1 flavodoxin FldB -
NWT75_RS03885 (786896) 786896..787792 + 897 WP_004144729.1 site-specific tyrosine recombinase XerD -
NWT75_RS03890 (787815) 787815..788528 + 714 WP_002916301.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NWT75_RS03895 (788534) 788534..790267 + 1734 WP_258336474.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16075.89 Da        Isoelectric Point: 11.4778

>T254416 WP_023290968.1 NZ_CP102893:785857-786267 [Klebsiella quasipneumoniae]
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
EWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDPGEWRDLRRLVLQKPAQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10480.98 Da        Isoelectric Point: 5.1116

>AT254416 WP_002916312.1 NZ_CP102893:785610-785876 [Klebsiella quasipneumoniae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDADKQLFIRLLENDDPDLFNWLMNHGKPADAELQRMVTLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N4VX63

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3GY41

References