Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1907402..1907547 Replicon chromosome
Accession NZ_CP102889
Organism Klebsiella pneumoniae strain KW2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1907438..1907540 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1907402..1907547 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWT79_RS09190 (NWT79_09190) 1902532..1904592 + 2061 WP_004151449.1 oligopeptidase B -
NWT79_RS09195 (NWT79_09195) 1904596..1905255 - 660 WP_002911407.1 exodeoxyribonuclease X -
NWT79_RS09200 (NWT79_09200) 1905334..1905564 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NWT79_RS09205 (NWT79_09205) 1905677..1906051 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NWT79_RS09210 (NWT79_09210) 1906055..1906924 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NWT79_RS09215 (NWT79_09215) 1906941..1907279 + 339 WP_075647430.1 YebY family protein -
- 1907402..1907547 - 146 - - Antitoxin
- 1907438..1907540 + 103 - - Toxin
NWT79_RS09220 (NWT79_09220) 1907916..1908059 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NWT79_RS09225 (NWT79_09225) 1908164..1909132 - 969 WP_014907334.1 VirK/YbjX family protein -
NWT79_RS09230 (NWT79_09230) 1909289..1909942 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
NWT79_RS09235 (NWT79_09235) 1909939..1910130 - 192 WP_002911395.1 YebW family protein -
NWT79_RS09240 (NWT79_09240) 1910228..1910467 - 240 WP_002911393.1 YebV family protein -
NWT79_RS09245 (NWT79_09245) 1910583..1912016 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254393 NZ_CP102889:1907438-1907540 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254393 NZ_CP102889:c1907547-1907402 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References