Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1936697..1936842 Replicon chromosome
Accession NZ_CP102869
Organism Klebsiella pneumoniae strain KA2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1936733..1936835 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1936697..1936842 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWT85_RS09460 (NWT85_09460) 1931827..1933887 + 2061 WP_004148850.1 oligopeptidase B -
NWT85_RS09465 (NWT85_09465) 1933891..1934550 - 660 WP_002911407.1 exodeoxyribonuclease X -
NWT85_RS09470 (NWT85_09470) 1934629..1934859 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NWT85_RS09475 (NWT85_09475) 1934972..1935346 + 375 WP_023285314.1 CopC domain-containing protein YobA -
NWT85_RS09480 (NWT85_09480) 1935350..1936219 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
NWT85_RS09485 (NWT85_09485) 1936236..1936574 + 339 WP_002911404.1 YebY family protein -
- 1936697..1936842 - 146 - - Antitoxin
- 1936733..1936835 + 103 - - Toxin
NWT85_RS09490 (NWT85_09490) 1937210..1937353 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NWT85_RS09495 (NWT85_09495) 1937458..1938426 - 969 WP_004151446.1 VirK/YbjX family protein -
NWT85_RS09500 (NWT85_09500) 1938583..1939236 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
NWT85_RS09505 (NWT85_09505) 1939233..1939424 - 192 WP_002911395.1 YebW family protein -
NWT85_RS09510 (NWT85_09510) 1939522..1939761 - 240 WP_002911393.1 YebV family protein -
NWT85_RS09515 (NWT85_09515) 1939877..1941310 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254332 NZ_CP102869:1936733-1936835 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254332 NZ_CP102869:c1936842-1936697 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References