Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2017297..2017568 Replicon chromosome
Accession NZ_CP102853
Organism Escherichia coli strain 573

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2017427..2017530 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2017297..2017568 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWH85_RS09820 2013852..2014514 - 663 WP_258334548.1 exodeoxyribonuclease X -
NWH85_RS09825 2014538..2015194 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
NWH85_RS09830 2015296..2015526 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NWH85_RS09835 2015665..2016039 + 375 WP_000204699.1 CopC domain-containing protein YobA -
NWH85_RS09840 2016043..2016915 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
NWH85_RS09845 2016928..2017269 + 342 WP_000976472.1 YebY family protein -
- 2017297..2017568 - 272 - - Antitoxin
- 2017427..2017530 + 104 - - Toxin
NWH85_RS09850 2017665..2018321 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NWH85_RS09855 2018322..2018513 - 192 WP_001296140.1 YebW family protein -
NWH85_RS09860 2018618..2018854 - 237 WP_001295499.1 YebV family protein -
NWH85_RS09865 2018972..2020411 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T254295 NZ_CP102853:2017427-2017530 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT254295 NZ_CP102853:c2017568-2017297 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References