Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2182812..2183319 Replicon chromosome
Accession NC_015738
Organism Eggerthella sp. YY7918

Toxin (Protein)


Gene name - Uniprot ID F7UVA6
Locus tag EGYY_RS09205 Protein ID WP_013980373.1
Coordinates 2182812..2183078 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag EGYY_RS09210 Protein ID WP_198408577.1
Coordinates 2183122..2183319 (+) Length 66 a.a.

Genomic Context

EGYY_RS09175EGYY_RS09180EGYY_RS09185EGYY_RS13420EGYY_RS09195EGYY_RS09205EGYY_RS09210EGYY_RS09220EGYY_RS09170EGYY_RS09200EGYY_RS09215EGYY_RS09225
Location: 2179282..2179569 (288 bp)
Type: Others
Protein ID: WP_013980367.1
Location: 2179557..2179916 (360 bp)
Type: Others
Protein ID: WP_151197466.1
Location: 2180031..2180345 (315 bp)
Type: Others
Protein ID: WP_013980369.1
Location: 2180342..2181055 (714 bp)
Type: Others
Protein ID: WP_013980370.1
Location: 2181039..2182226 (1188 bp)
Type: Others
Protein ID: WP_013980371.1
Location: 2182812..2183078 (267 bp)
Type: Toxin
Protein ID: WP_013980373.1
Location: 2183122..2183319 (198 bp)
Type: Antitoxin
Protein ID: WP_198408577.1
Location: 2185447..2186730 (1284 bp)
Type: Others
Protein ID: WP_013980376.1
Location: 2178682..2178993 (312 bp)
Type: Others
Protein ID: WP_013980366.1
Location: 2182346..2182636 (291 bp)
Type: Others
Protein ID: WP_013980372.1
Location: 2183339..2185363 (2025 bp)
Type: Others
Protein ID: WP_013980375.1
Location: 2186727..2188040 (1314 bp)
Type: Others
Protein ID: WP_013980377.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EGYY_RS091702178682..2178993-312WP_013980366.1Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC-
EGYY_RS091752179282..2179569+288WP_013980367.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-
EGYY_RS091802179557..2179916+360WP_151197466.1type II toxin-antitoxin system PemK/MazF family toxin-
EGYY_RS091852180031..2180345+315WP_013980369.1PadR family transcriptional regulator-
EGYY_RS134202180342..2181055+714WP_013980370.1DUF1700 domain-containing protein-
EGYY_RS091952181039..2182226+1188WP_013980371.1DUF4097 family beta strand repeat protein-
EGYY_RS092002182346..2182636-291WP_013980372.1hypothetical protein-
EGYY_RS092052182812..2183078+267WP_013980373.1BrnT family toxinToxin
EGYY_RS092102183122..2183319+198WP_198408577.1CopG family transcriptional regulatorAntitoxin
EGYY_RS092152183339..2185363-2025WP_013980375.1ATP-dependent DNA helicase-
EGYY_RS092202185447..2186730+1284WP_013980376.1serpin family protein-
EGYY_RS092252186727..2188040-1314WP_013980377.1amidohydrolase family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10240.55 Da        Isoelectric Point: 9.4003

>T25429 WP_013980373.1 NC_015738:2182812-2183078 [Eggerthella sp. YY7918]
MKFEYDPAKSAGNLIKHGIDFEKAQELWNSKTIELESKAYVSEHRTLVLGKIEGKHWTAIVTERGDATRIISVRRSRQKE
ARYYDETN

Download         Length: 267 bp

>T25429 NC_015738:2182812-2183078 [Eggerthella sp. YY7918]
ATGAAGTTTGAATATGACCCAGCAAAAAGTGCAGGCAACCTTATCAAACACGGCATAGACTTCGAAAAAGCTCAAGAACT
TTGGAATAGTAAAACAATAGAACTAGAATCAAAAGCATATGTTAGCGAGCATCGTACCCTCGTTCTGGGAAAGATAGAGG
GAAAGCACTGGACAGCTATCGTTACCGAACGTGGTGACGCAACGCGAATCATCTCCGTCAGGCGCTCAAGACAGAAGGAG
GCGCGCTATTATGACGAAACAAATTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7793.91 Da        Isoelectric Point: 6.7237

>AT25429 WP_198408577.1 NC_015738:2183122-2183319 [Eggerthella sp. YY7918]
MDHFDVRHPIIRNDGSVRRVSVDMPEWMIEQLDDEARHLAVPRQAIIKIWLSERLERQSQARQMS

Download         Length: 198 bp

>AT25429 NC_015738:2183122-2183319 [Eggerthella sp. YY7918]
ATGGACCACTTTGACGTAAGGCACCCTATTATAAGAAACGACGGCAGTGTACGACGCGTAAGTGTCGACATGCCCGAATG
GATGATCGAGCAACTCGACGACGAGGCTCGACACTTAGCCGTCCCTCGTCAGGCAATTATTAAAATATGGCTTTCTGAGC
GACTTGAAAGACAGAGCCAAGCTCGACAAATGTCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBF7UVA6

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References