Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4062749..4063278 Replicon chromosome
Accession NZ_CP102850
Organism Gordonia mangrovi strain HNM0687

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NWF22_RS18500 Protein ID WP_160903141.1
Coordinates 4063015..4063278 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NWF22_RS18495 Protein ID WP_160903140.1
Coordinates 4062749..4063015 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWF22_RS18465 (NWF22_18465) 4057771..4058943 + 1173 WP_160903135.1 cystathionine gamma-synthase -
NWF22_RS18470 (NWF22_18470) 4058960..4060156 + 1197 WP_160903136.1 threonine ammonia-lyase -
NWF22_RS18475 (NWF22_18475) 4060178..4060696 - 519 WP_160903387.1 SRPBCC family protein -
NWF22_RS18480 (NWF22_18480) 4060898..4061776 + 879 WP_160903137.1 phosphatase PAP2 family protein -
NWF22_RS18485 (NWF22_18485) 4061683..4062039 - 357 WP_160903138.1 hypothetical protein -
NWF22_RS18490 (NWF22_18490) 4062165..4062740 + 576 WP_160903139.1 hypothetical protein -
NWF22_RS18495 (NWF22_18495) 4062749..4063015 + 267 WP_160903140.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NWF22_RS18500 (NWF22_18500) 4063015..4063278 + 264 WP_160903141.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NWF22_RS18505 (NWF22_18505) 4063358..4065202 - 1845 WP_160903142.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10009.64 Da        Isoelectric Point: 10.9259

>T254286 WP_160903141.1 NZ_CP102850:4063015-4063278 [Gordonia mangrovi]
MMYRVQLAPSAVRSLDRLSPRYVHAVIDFIYGPLAQNPRRVGKPLGGNLLGFYSARRGAYRVIYELPDDATVLVIRVDHR
AHVYRQR

Download         Length: 264 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9788.98 Da        Isoelectric Point: 4.6652

>AT254286 WP_160903140.1 NZ_CP102850:4062749-4063015 [Gordonia mangrovi]
VRILPLSVAKAKLSELVDEVMRTHEHVTVTRNGSAAVVLVSADEWDAVQETLYWQSRPGLADDIREAREALADESTLDEA
AVRARYAR

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References