254284

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 1981000..1981652 Replicon chromosome
Accession NZ_CP102850
Organism Gordonia mangrovi strain HNM0687

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NWF22_RS09120 Protein ID WP_160904624.1
Coordinates 1981000..1981389 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NWF22_RS09125 Protein ID WP_160904623.1
Coordinates 1981386..1981652 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWF22_RS09095 (NWF22_09095) 1976336..1977235 - 900 WP_160904629.1 SMP-30/gluconolactonase/LRE family protein -
NWF22_RS09100 (NWF22_09100) 1977324..1978562 - 1239 WP_160904628.1 cytochrome P450 -
NWF22_RS09105 (NWF22_09105) 1978818..1979735 + 918 WP_160904627.1 alpha/beta hydrolase -
NWF22_RS09110 (NWF22_09110) 1979761..1980066 + 306 WP_160904626.1 EthD family reductase -
NWF22_RS09115 (NWF22_09115) 1980241..1980981 + 741 WP_160904625.1 FCD domain-containing protein -
NWF22_RS09120 (NWF22_09120) 1981000..1981389 - 390 WP_160904624.1 type II toxin-antitoxin system VapC family toxin Toxin
NWF22_RS09125 (NWF22_09125) 1981386..1981652 - 267 WP_160904623.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NWF22_RS09130 (NWF22_09130) 1981882..1985148 + 3267 WP_160904635.1 AfsR/SARP family transcriptional regulator -
NWF22_RS09135 (NWF22_09135) 1985141..1985608 - 468 WP_160904622.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-115)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13736.68 Da        Isoelectric Point: 4.8451

>T254284 WP_160904624.1 NZ_CP102850:c1981389-1981000 [Gordonia mangrovi]
VSLTYVDTSAAMKLIVDEPESEPLLSSLTSAPARRLIASWLLHAELHCAAGRYPDVVSPEALSAVLATIDLIDLTRGDMI
AAGTYAPLRSHDAIHLAVAIRVGADDFLTYDDELAARASRAGLRALSPR

Download         Length: 390 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10068.35 Da        Isoelectric Point: 7.3232

>AT254284 WP_160904623.1 NZ_CP102850:c1981652-1981386 [Gordonia mangrovi]
MESVTHREMRNRSAELLRRVEAGESIIVTNNGRPVAVISPLERRVLEELVDQGHVRRATRAVADLRDIERTASALRTDQI
LDDTRGHW

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References