Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Rv0298-Rv0299/-
Location 1025353..1025879 Replicon chromosome
Accession NZ_CP102850
Organism Gordonia mangrovi strain HNM0687

Toxin (Protein)


Gene name Rv0299 Uniprot ID -
Locus tag NWF22_RS04740 Protein ID WP_258321324.1
Coordinates 1025634..1025879 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name Rv0298 Uniprot ID -
Locus tag NWF22_RS04735 Protein ID WP_160900404.1
Coordinates 1025353..1025580 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWF22_RS04715 (NWF22_04715) 1020757..1021149 - 393 WP_160900406.1 hypothetical protein -
NWF22_RS04720 (NWF22_04720) 1021235..1023820 - 2586 WP_160901363.1 helix-turn-helix transcriptional regulator -
NWF22_RS04725 (NWF22_04725) 1024411..1024866 + 456 WP_160900405.1 helix-turn-helix domain-containing protein -
NWF22_RS04730 (NWF22_04730) 1024872..1025129 + 258 WP_258321323.1 PIN domain-containing protein -
NWF22_RS04735 (NWF22_04735) 1025353..1025580 + 228 WP_160900404.1 ribbon-helix-helix protein, CopG family Antitoxin
NWF22_RS04740 (NWF22_04740) 1025634..1025879 + 246 WP_258321324.1 toxin Toxin
NWF22_RS04745 (NWF22_04745) 1026012..1026800 - 789 WP_160900402.1 alpha/beta hydrolase -
NWF22_RS04750 (NWF22_04750) 1026914..1028425 + 1512 WP_160900401.1 LuxR C-terminal-related transcriptional regulator -
NWF22_RS04755 (NWF22_04755) 1028493..1029317 + 825 WP_160900400.1 alpha/beta hydrolase -
NWF22_RS04760 (NWF22_04760) 1029245..1030810 - 1566 WP_160900399.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 997531..1069968 72437


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Ribbon-helix-helix protein, CopG

(6-41)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8327.80 Da        Isoelectric Point: 3.8792

>T254282 WP_258321324.1 NZ_CP102850:1025634-1025879 [Gordonia mangrovi]
VVLSNSIHIAADTGRIIVCPYIPGPIPEGTMAMVVAVGEPEGVALPELVQWLPVTALDDPIGNIGAEALRQAVGLMTALI
T

Download         Length: 246 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8097.17 Da        Isoelectric Point: 6.4761

>AT254282 WP_160900404.1 NZ_CP102850:1025353-1025580 [Gordonia mangrovi]
MAKDKVSITLDSAVLATADADAKAAGLNRSELIERALRHEHLRIALTNYTTHTVPALNIDDYADMIHQANKAAGL

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References