Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 963645..964198 Replicon chromosome
Accession NZ_CP102850
Organism Gordonia mangrovi strain HNM0687

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NWF22_RS04525 Protein ID WP_160900438.1
Coordinates 963645..963926 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NWF22_RS04530 Protein ID WP_160900437.1
Coordinates 963923..964198 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWF22_RS04510 (NWF22_04510) 960074..961138 - 1065 WP_233750863.1 LLM class F420-dependent oxidoreductase -
NWF22_RS04515 (NWF22_04515) 961364..962479 + 1116 WP_258321321.1 o-succinylbenzoate--CoA ligase -
NWF22_RS04520 (NWF22_04520) 962592..963593 + 1002 WP_160900439.1 putative zinc-binding metallopeptidase -
NWF22_RS04525 (NWF22_04525) 963645..963926 - 282 WP_160900438.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NWF22_RS04530 (NWF22_04530) 963923..964198 - 276 WP_160900437.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NWF22_RS04535 (NWF22_04535) 964328..965449 - 1122 WP_160900436.1 linear amide C-N hydrolase -
NWF22_RS04540 (NWF22_04540) 965708..969175 + 3468 WP_160900435.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(17-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10520.98 Da        Isoelectric Point: 10.6733

>T254281 WP_160900438.1 NZ_CP102850:c963926-963645 [Gordonia mangrovi]
MSDSTPQPYDVAIASPARRALSRLPGRVAHAVIEFISGPLAENPRRLSKPLRNQLDGLHSARRGDYRILLRIDDDNRTVL
IVDIDHRAHVYRT

Download         Length: 282 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9651.80 Da        Isoelectric Point: 4.6365

>AT254281 WP_160900437.1 NZ_CP102850:c964198-963923 [Gordonia mangrovi]
MTTVPLGEAKDKLSALVDSAESTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRRGTAEAVAAADDESAAGKTISLD
DLRAEHGLPPR

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References